N/A
Completed N=344
Bright IDEAS - Young Adults Problem-Solving Skills Training
Cancer Patients · Young Adult · Supportive Care
Source: ClinicalTrials.gov NCT04585269 ↗
Enrolled (actual)
344
Serious AEs
2.6%
Results posted
Nov 2025
Primary outcomePrimary: Change in Symptoms of Depression, as Measured by the Patient-Reported Outcomes Measurement Information System (PROMIS) Depression Short-Form (v1.0 8a) — -2.92; 0.31 T-score points — p=<0.001
Summary
The purpose of this project is to evaluate efficacy of Bright IDEAS, an evidence-based problem-solving skills training (PSST) program, as a supportive care intervention for young adult (YA) cancer patients compared with enhanced usual psychosocial care with 344 young adult patients newly diagnosed with cancer.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Symptoms of Depression, as Measured by the Patient-Reported Outcomes Measurement Information System (PROMIS) Depression Short-Form (v1.0 8a) |
-2.92; 0.31 | <0.001 sig |
| PRIMARY Change in Symptoms of Anxiety, as Measured by the PROMIS Anxiety Short-Form (v1.0 8a) |
-2.21; 0.22 | 0.003 sig |
| PRIMARY Change in Functional Assessment of Cancer Therapy - General (FACT-G v4) |
6.06; 2.66 | 0.029 sig |
| SECONDARY Symptoms of Depression, as Measured by the Patient-Reported Outcomes Measurement Information System (PROMIS) Depression Short-Form (v1.0 8a) |
— | — |
| SECONDARY Symptoms of Anxiety, as Measured by the PROMIS Anxiety Short-Form (v1.0 8a) |
— | — |
| SECONDARY Functional Assessment of Cancer Therapy - General (FACT-G v4) |
— | — |
Eligibility Criteria
Inclusion Criteria
- Current age 18-39
- Within 4 months of first diagnosis of any cancer
- Cancer being treated with chemotherapy and/or radiation therapy and/or hematopoietic stem cell transplant
- No documented or self-reported cognitive delay or impairment that would prevent completion of survey measures
- English-speaking
Exclusion Criteria
- Medical crisis or not receiving curative therapy per physician/treatment team report
- Treatment involves surgery only
Data sourced from ClinicalTrials.gov (NCT04585269). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.