N/A
N=37
Cigarette Smoking Decision Study
Tobacco Smoking
Bottom Line
View on ClinicalTrials.gov: NCT04595279 ↗Enrolled (actual)
37
Serious AEs
0.0%
Results posted
Jun 2025
Primary outcome: Primary: Demand Intensity as Assessed by a Behavioral Economic Demand Curve — 4.709677419; 2.580645161 puff bouts
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Smoking sessions (Behavioral)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- Johns Hopkins University
- Primary completion
- Mar 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Demand Intensity as Assessed by a Behavioral Economic Demand Curve |
4.709677419; 2.580645161 | — |
| PRIMARY Demand Elasticity as Assessed by a Behavioral Economic Demand Curve |
— | — |
| PRIMARY Cross-price Elasticity Coefficients as Assessed by a Behavioral Economic Demand Curve |
0.03; 0.05 | — |
| PRIMARY Change in Total Puff Volume as Measured by a Smoking Topography Machine |
1649; 1321 | — |
Summary
The Family Smoking Prevention and Tobacco Control Act granted the FDA the authority to regulate and restrict tobacco advertising tactics that inaccurately convey reduced product risk, yet there is a dearth of up-to-date regulatory science to inform such regulations. Although the FDA has restricted use of descriptors such as "natural" and "additive-free," research shows that the tobacco industry quickly pivoted to increase use of alternative, unregulated tactics. Greenwashing is one increasingly common tobacco marketing strategy in which products are portrayed as eco-friendly and/or natural. The investigators' preliminary research indicates that greenwashing tactics may inaccurately convey modified product risk to consumers. The overarching objective of this project is to test the effect of greenwashing methods used by cigarette companies to market products on actual smoking behavior in a controlled laboratory study. The investigators' proposed research focuses on young adults (age 18-29), because this is a key age for smoking initiation and escalation, and research has found that young adults may be more susceptible than older adults to greenwashing in cigarette ads. This study will test the effect of greenwashing on behavioral economic demand and smoking topography in a laboratory-controlled cigarette self-administration study. These data will clearly connect tobacco advertising features to product risk perceptions and actual smoking behavior. This work will provide FDA with an integrated set of evidence that identifies misleading greenwashing tactics that inaccurately convey modified product risk which can be used to inform regulatory action regarding restrictions of this type of advertising.
Eligibility Criteria
Inclusion Criteria
- Age 18 - 29 years of age
- Smoke at least five cigarettes per day
- Have an expired carbon monoxide level of more than 8 ppm or a urinary cotinine level of more than 100 ng per milliliter
Exclusion Criteria
- The intention to quit smoking in the next 30 days
- Report "roll your own" cigarettes as an exclusive form of smoking
- A serious medical or psychiatric disorder or unstable condition
- Any positive toxicological screening for illicit drugs other than cannabis will be excluded
- Women who are pregnant, plan to become pregnant or are breast-feeding
Data sourced from ClinicalTrials.gov (NCT04595279). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.