Phase 4 N=41 Randomized Double-blind Prevention

Evaluation of Aerosol in a Dental Clinic

Covid19

Bottom Line

View on ClinicalTrials.gov: NCT04659928 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jul 2025

Primary outcome: Primary: Number of Bacterial Colony Forming Units (CFUs) — 47.2; 125.3; 70.7; 116.7 bacterial colony forming units (CFUs)

Study Design & Population

Study type: Interventional
Phase: Phase 4
Interventions: High volume evacuation (HVE) (Device); Extraoral vacuum aspirator (EVA) (Device); Hydrogen Peroxide (Drug); Placebo (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: The University of Texas Health Science Center, Houston
Primary completion: May 2024

Outcome Measures

Outcome	Result	p-value
PRIMARY Number of Bacterial Colony Forming Units (CFUs)	101.3; 87.1; 45.7; 52.44	—
PRIMARY Number of Bacterial Colony Forming Units (CFUs)	101.3; 87.1; 45.7; 52.44	—
SECONDARY Number of Bacterial Colony Forming Units (CFUs) at Each Location	31.4; 31.3; 2.9; 3.44; 9.4; 16.9	—
SECONDARY Number of Bacterial Colony Forming Units (CFUs) at Each Location	31.4; 31.3; 2.9; 3.44; 9.4; 16.9	—

Summary

The purpose of this study is to evaluate the effectiveness of external evacuation units and mouth rinses during aerosol generating procedures in a dental clinic and to determine the risk level to the dental practitioners during aerosol generating procedures.

Eligibility Criteria

Inclusion Criteria

prepping natural teeth at the appointment
at least an hour long procedure
procedure will be the first one in the morning

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04659928). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.