N/A
N=44
Predictors of Recovery and the App-Facilitated Tele-Rehabilitation (AFTER) Program for COVID-19 Survivors
Covid-19 · Deconditioning
Bottom Line
View on ClinicalTrials.gov: NCT04663945 ↗Enrolled (actual)
44
Serious AEs
6.8%
Results posted
Nov 2022
Primary outcome: Primary: Adherence (Primary Feasibility/Safety Outcome) — 93 % of participants meeting adherence
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Biobehavioral Tele-rehabilitation Sessions (Behavioral)
- Age
- Adult, Older Adult · 35+ yrs
- Sex
- All
- Sponsor
- University of Colorado, Denver
- Primary completion
- Aug 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Adherence (Primary Feasibility/Safety Outcome) |
93 | — |
| PRIMARY Change in 30 Second Chair Stand Test (Primary Efficacy Outcome) |
3.1; 5.0; 3.2; 5.1 | — |
| SECONDARY System Usability Scale (SUS) |
72 | — |
| SECONDARY Safety Event Count |
0; 1; 11; 9 | — |
| SECONDARY Timed Up-and-Go Test (TUG) |
-1.7; -0.6; -1.9; -0.6 | — |
| SECONDARY 4-Stage Balance Test |
1.8; 1.6; 2.9; 2.7 | — |
| SECONDARY MRC Dyspnea |
-1.3; -1.2; -1.5; -1.4 | — |
| SECONDARY Activities-Specific Balance Confidence (ABC) Scale |
7.1; 11.3; 10.0; 14.2 | — |
| SECONDARY Three-Item Loneliness Scale |
-0.4; 0.3; -0.8; -0.1 | — |
| SECONDARY PROMIS Short Form (SF) v1.0 General Self-Efficacy 4a |
-0.3; -0.2; 0.1; 0.2 | — |
| SECONDARY PROMIS Short Form (SF) Self-Efficacy for Managing Chronic Conditions |
2.2; 2.7; 3.9; 4.4 | — |
| SECONDARY PROMIS Scale v1.2 Global Health: |
0.5; 2.1; 3.0; 4.6 | — |
| SECONDARY Montreal Cognitive Assessment (MoCA)-BLIND |
1.1; 0.5 | — |
| SECONDARY Clinical Frailty Scale |
-0.5; -0.4; -0.8; -0.7 | — |
| SECONDARY Average Daily Step Count |
56; 56; 6; 6 | — |
| SECONDARY Patient Health Questionnaire 8 (PHQ8) |
-3.8; -1.9; -5.0; -3.1 | — |
Summary
The aim of this study is to investigate the feasibility (safety, adherence) and initial efficacy (physical function and patient reported outcomes) of a multicomponent tele-rehabilitation program during COVID-19 recovery of patients who have been hospitalized due to COVID-19.
Eligibility Criteria
Inclusion Criteria
- Confirmed COVID-19, per diagnostic criteria (PCR testing)
- Hospitalized for at least 24 hours
- Able to provide informed consent
- Internet capability to access the platform
- Community-dwelling prior to hospitalization
Exclusion Criteria
- Unstable medical comorbidities that would preclude participation in exercise
- Receipt of >1 session of outpatient physical therapy
- Known pregnancy, as the impact on physical function, pulmonary function, and other outcomes will vary well beyond any expected effects of COVID-19
- Anticipating concurrent additional physical therapy services during study intervention period (12 weeks)
Data sourced from ClinicalTrials.gov (NCT04663945). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.