N/A
Completed N=10
N-of-few Study of Pain Perception
Healthy
Source: ClinicalTrials.gov NCT04664400 ↗
Enrolled (actual)
10
Serious AEs
0.0%
Results posted
Nov 2022
Primary outcomePrimary: Within Participant Subjective Ratings of Acute Thermal Pain Following High Compared to Low Cues (Learned Via Symbolic Learning) — 7.32 score on a scale — p=0.043
Summary
A behavioral study that will examine how pain perception is affected by different types of conditioning and by context, with a few participants and multiple sessions ("N-of-few" design).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Within Participant Subjective Ratings of Acute Thermal Pain Following High Compared to Low Cues (Learned Via Symbolic Learning) |
7.32 | 0.043 sig |
| PRIMARY Within Participant Subjective Ratings of Acute Thermal Pain Following High Compared to Low Cues (Learned Via Conditioning) |
13.21 | 0.036 sig |
| PRIMARY Within Participant Subjective Ratings of Acute Thermal Pain Following High Compared to Low Cues (Learned Via Instructions Only) |
13.76 | 0.012 sig |
| PRIMARY Within Participant Subjective Ratings of Acute Thermal Pain, When it is the Worse vs. the Better Alternative |
-2.06 | 0.835 |
Eligibility Criteria
Inclusion Criteria
- Healthy participants
Exclusion Criteria
- Cannot tolerate heat pain applied to the forearm/leg, based on a calibration task at the beginning of the experiment
Data sourced from ClinicalTrials.gov (NCT04664400). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.