N/A
N=12
Comparing MRI to CT on Pediatric Craniosynostosis.
Craniosynostosis
Bottom Line
View on ClinicalTrials.gov: NCT04704284 ↗Enrolled (actual)
12
Serious AEs
0.0%
Results posted
Jul 2025
Primary outcome: Primary: Number of Participants With 90% or Greater Concordance Between ZTE and CT Imaging Diagnosis — 9 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Zero Echo Time Magnetic Resonance Imaging (ZTE MRI) (Diagnostic_test)
- Age
- Pediatric, Adult
- Sex
- All
- Sponsor
- Mayo Clinic
- Primary completion
- May 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With 90% or Greater Concordance Between ZTE and CT Imaging Diagnosis |
9 | — |
Summary
The purpose of this study is to develop and test the effectiveness and diagnostic quality of Zero Echo Time Magnetic Resonance Imaging (ZTE MRI) in comparison to CT.
Eligibility Criteria
Inclusion Criteria
- Pediatric patients 0-18 of age will be recruited by our surgical colleagues based on the clinical concern for craniosynostosis and possible need for calvarial reconstruction.
Exclusion Criteria
- Lack of consent
- Contraindication/inability to undergo both examinations within the designated time period and/or undiagnostic image quality.
Data sourced from ClinicalTrials.gov (NCT04704284). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.