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N/A N=36 Randomized Supportive Care

A Telehealth Advance Care Planning Intervention for Older Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome

Acute Myeloid Leukemia · Myelodysplastic Syndromes

Enrolled (actual)
36
Serious AEs
0.0%
Results posted
Feb 2025
Primary outcome: Primary: Feasibility - Retention Rate — 19; 6; 10 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Telehealth (Behavioral); Control (Behavioral)
Age
Adult, Older Adult · 60+ yrs
Sex
All
Sponsor
University of Rochester
Primary completion
Mar 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Feasibility - Retention Rate
19; 6; 10
PRIMARY
Recruitment Rate
21; 6; 10
PRIMARY
Mean Usability of the Telehealth Advance Care Planning Intervention Using the Telehealth Usability Questionnaire (TUQ)
5.9; 5.9
SECONDARY
Pre- and Post-Intervention Change of the Mean Score for the General Anxiety Disorder-7 (GAD-7)
0.1; -2.8
SECONDARY
Pre- and Post-Intervention Change of the Mean Score for the Patient Health Questionnaire-9 (PHQ-9)
0.4; -1.0
SECONDARY
Pre- and Post-Intervention Change of the Mean Score for the Distress Thermometer
0.3; -1.3
SECONDARY
Pre- and Post-Intervention Change of the Mean Score for the Functional Assessment of Cancer Therapy-Leukemia (FACT-Leu)
-3.3
SECONDARY
Post-Intervention Mean Score for the Health Care Communication Questionnaire (HCCQ)
18.3; 18.2

Summary

This is a pilot study to evaluate the usability and feasibility of a telehealth-delivered advance care planning intervention among 20 older patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS).

Eligibility Criteria

Inclusion Criteria for Patients:

  • Age ≥60 years (conventional definition of older age in AML/MDS)
  • AML or MDS diagnosis
  • Being managed in the outpatient settings
  • Able to provide informed consent
  • English-speaking

Exclusion Criteria: N/A

Inclusion Criteria for Caregivers

  • Age ≥21 years
  • Selected by patient when asked if there is a "family member, partner, friend, or caregiver with whom you discuss or who can be helpful in health-related matters"
  • Able to provide informed consent
  • English-speaking

Exclusion Criteria: N/A

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04745676). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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