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N/A N=551 Randomized Health Services Research

Evaluation of an Automated Physician-Directed Messaging on Patient Engagement in the Digital Diabetes Prevention Program

Pre Diabetes

Enrolled (actual)
551
Serious AEs
0.0%
Results posted
Jan 2026
Primary outcome: Primary: Change in Hemoglobin A1c (HbA1c) Level (mmol/Mol) — 0.02; -0.03 mmol/mol

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Digital diabetes prevention program (dDPP) (Other); Adapted dDPP-EHR tool (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
NYU Langone Health
Primary completion
Jan 2025

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Hemoglobin A1c (HbA1c) Level (mmol/Mol)
0.01; 0.01
PRIMARY
Change in Hemoglobin A1c (HbA1c) Level (mmol/Mol)
0.01; 0.01
PRIMARY
Change in Body Weight (Lbs)
-7.42; -7.02
PRIMARY
Change in Body Weight (Lbs)
-7.42; -7.02
PRIMARY
Change in Body Mass Index (BMI) (Lbs/in^2)
1.2045; -1.16
PRIMARY
Change in Body Mass Index (BMI) (Lbs/in^2)
1.2045; -1.16
SECONDARY
Engagement With the dDPP Platform
0.29; 0.25
SECONDARY
Engagement With the dDPP Platform
0.29; 0.25

Summary

This study aims to understand the effects of automated physician directed messaging on patient engagement in the digital diabetes prevention program (dDPP). The messages are tailored to patient engagement levels based on established engagement thresholds, which are based on the patient's use of the dDPP application. The system is designed to minimize work for providers by sending automated targeted messages to patients to potentially increase engagement, prevent onset of diabetes and improve clinical outcomes. The patients in the study are automatically nudged using a combination of text messaging and MyChart messaging.

Eligibility Criteria

Inclusion Criteria

  • 18 years or older, BMI ≥ 25 kg/m2 (> 22 kg/m2 if self-identified as Asian)
  • Must be a NYU Langone patient
  • A diagnosis of prediabetes (either diagnosis of prediabetes or an HbA1C level of 5.7%-6.4% in past 12 months) or diabetes risk factors (BMI ≥ 25 kg/m2 or > 22 kg/m2 if self-identified as Asian
  • Safe to engage in moderate physical exercise (as determined by their PCP)
  • Sufficient English to be able to complete the enrollment process
  • Has app-capable device with data to use the dDPP application and receive text messages

Exclusion Criteria

  • Diagnosed with diabetes
  • Patients whose weight may vary considerably over the study's timeframe for reasons other than the intervention (e.g. cancer, pregnancy, ascites, severe CHF)
  • Patients with severe psychiatric disease or dementia
  • Active health condition that prevents them from engaging in moderate exercise
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04773834). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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