N/A
N=792
COVID-19 Self-Testing Through Rapid Network Distribution
Covid19
Bottom Line
View on ClinicalTrials.gov: NCT04797858 ↗Enrolled (actual)
792
Serious AEs
0.0%
Results posted
May 2025
Primary outcome: Primary: Network Contact Test Uptake — 5; 2 Participants — p=0.45
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- COVID-19 self-test (Behavioral); COVID-19 test referral (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Pennsylvania
- Primary completion
- Nov 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Network Contact Test Uptake |
5; 2 | 0.45 |
| SECONDARY Network Contact Test Uptake, End of Study |
8; 2 | 0.11 |
| SECONDARY Number of Contacts Tested at 8 Weeks |
23; 13 | — |
| SECONDARY Number of Contacts Tested |
31; 16 | — |
| SECONDARY Number of Participants With at Least One Network Contact Who Tested Positive for COVID-19 at 8 Weeks |
3; 0 | — |
| SECONDARY Number of Participants With at Least One Network Contact Who Tested Positive for COVID-19, End of Study |
3; 0 | — |
Summary
COVID-19, the coronavirus disease caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has led to a global pandemic and has exacerbated existing health inequities among vulnerable populations. Despite higher rates of COVID-19 in Black and Latinx individuals compared to White individuals, rates of testing in predominately non-White, low-income communities are significantly lower than in high-income areas. Self-testing, where individuals collect their own samples, is now feasible for the detection of SARS-CoV-2. One promising approach to increase test uptake is the secondary distribution of self-testing kits, where an individual distributes tests to contacts in their social network and encourages them to self-test.
The central hypothesis of this clinical trial is that the secondary distribution of SARS-CoV-2 self-tests can significantly expand test uptake among underserved populations. To test this hypothesis, the investigators will conduct a 1:1 randomized controlled trial that will assess a self-testing intervention that promotes the secondary distribution of SARS-CoV-2 test kits compared with test referrals, with a focus on reaching underserved populations.
Eligibility Criteria
Inclusion Criteria
- 18 years of age or older
- Has a working telephone number
- Willing and able to provide informed consent
Exclusion Criteria
- Younger than 18 years of age
- Does not have a working telephone number
- Prior COVID-19 infection in the past 90 days
- Previously received a COVID-19 test as part of this COVID-19 research study
- Unable or unwilling to provide informed consent
Data sourced from ClinicalTrials.gov (NCT04797858). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.