N/A
Completed N=5
Effects of Smoking State on Decision Making
Behavior
Source: ClinicalTrials.gov NCT04826276 ↗
Enrolled (actual)
5
Serious AEs
0.0%
Results posted
May 2026
Primary outcomePrimary: Effort Based Decision Making — 29.5; 18.3 high effort selections
Summary
Adult smokers will be tested using behavioral and neuroimaging measures after smoking as usual and after overnight abstinence.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Effort Based Decision Making |
29.5; 18.3 | — |
| PRIMARY Distress Tolerance Behavior |
615883; 24448 | — |
Eligibility Criteria
Inclusion Criteria
- Aged 18-55 years
- Smokes cigarettes or e-cigarettes
- Negative urine drug screen
Exclusion Criteria
- Unstable or serious medical or mental health condition
- History of serious head trauma
- Pregnancy
- Unsuitable for MRI
- Weight > 350 pounds (maximum allowed for MRI)
Data sourced from ClinicalTrials.gov (NCT04826276). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.