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Phase 4 Completed N=600 Randomized Treatment

Premature Discontinuation of Contraceptive Implants

Contraception Behavior
Source: ClinicalTrials.gov NCT04828824 ↗
Enrolled (actual)
600
Serious AEs
0.0%
Results posted
Apr 2026
Primary outcomePrimary: Number of Participants With Implant Continuation — 219; 225 Participants
◆ Published Evidence
No publication linked

No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.

Summary

To compare rates of etonogestrel implant discontinuation in implant initiators who are given advance provision of combined oral contraceptive pills (COCs) and a bleeding rescue regimen (COCR intervention) to participants given standard counseling (comparator).

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants With Implant Continuation
219; 225
SECONDARY
Overall Satisfaction With Contraceptive Implant
11; 9; 16; 16; 24; 20

Eligibility Criteria

Inclusion Criteria

  • You are between ages of 14 to 22.9 years.
  • Started etonogestrel implant for the first time and have never used the implant before.

Exclusion Criteria

  • There is any contraindication to estrogen containing birth control.
  • Desire of pregnancy in next 12 months.
  • Plans to move from the area in next 12 months and is not able to come to the clinic.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04828824). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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