N/A
N=81
Translational Research to Inform Interventions for Challenging Behavior
Behavior and Behavior Mechanisms
Bottom Line
View on ClinicalTrials.gov: NCT04842500 ↗Enrolled (actual)
81
Serious AEs
0.0%
Results posted
Feb 2025
Primary outcome: Primary: Peak Response Rate During Extinction — 1.58; 0.85; 1.3; 0.43 Proportion of baseline (frequency)
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Demand Informed Moderator Analysis (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Vanderbilt University
- Primary completion
- May 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Peak Response Rate During Extinction |
1.58; 0.85; 1.3; 0.43 | — |
| PRIMARY Schedule Value at Breakpoint |
16.45; 15.14; 16.94; 18.82 | — |
| PRIMARY The Schedule Value Designated as Pmax |
7.6; 7.32; 9; 7.71 | — |
| PRIMARY Response Latency |
213.3; 96; 467.4; 119.8 | — |
| SECONDARY Number of Sessions in Extinction |
1.2; 1.05; 1.89; 1.06 | — |
| SECONDARY Overall Session Duration |
630.87; 687.84; 668.89; 788.88 | — |
Summary
This project is meant to identify relations between the reinforcement histories of 80 adults with intellectual and developmental disabilities (IDD) and the prevalence of extinction bursts. Extinction bursts, or temporary increases in rates and intensities of behavior during extinction, often preclude the inclusion of extinction in intervention packages meant to suppress severe challenging behavior, despite the fact that extinction is often necessary to generate therapeutic outcomes. Study results will provide insight into how researchers can enhance interventions for the severe challenging behavior of individuals with IDD while mitigating the undesirable collateral effects (i.e., extinction bursts) of therapeutic action (i.e., extinction). Expanded access to study results will be made available to those who inquire after all data have been obtained and analyzed.
Eligibility Criteria
Inclusion Criteria
- Participants must be older than 18.
- Participants must have a developmental disability (unconstrained to specific diagnoses).
- Participants must be able to correctly manipulate all items used in the study.
- Participants must consent (or assent, when relevant) to procedures prior to and throughout the study.
Exclusion Criteria
- Participants younger than 18.
- Participants without disabilities.
- Participants who cannot correctly manipulate items used in the study.
- Participants who do not consent (or assent, when relevant) to participation.
Data sourced from ClinicalTrials.gov (NCT04842500). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.