N/A
N=110
Comparison of Different Ventilator and Vaporizer Technologies to Study Economic and Environmental Implications
Anesthetic Gas Consumption and Cost-Effectiveness
Bottom Line
View on ClinicalTrials.gov: NCT04851314 ↗Enrolled (actual)
110
Serious AEs
0.0%
Results posted
Aug 2021
Primary outcome: Primary: Primary Study Variable: Amount of Gas Vaporized Anesthetic Per Minute Anesthesia — 95.48; 119.3 grams/minute
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- ICU certified ventilator (Device); Non-ICU certified ventilator (Device)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of California, Irvine
- Primary completion
- Nov 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Primary Study Variable: Amount of Gas Vaporized Anesthetic Per Minute Anesthesia |
95.48; 119.3 | — |
| SECONDARY Time to Reach Aldrete > 8 |
98.13; 89.18 | — |
| SECONDARY Time to Extubation From Weaning |
10.37; 10.78 | — |
Summary
The purpose of this study is to test whether or not the use of a low volume ventilator in an anesthesia machine reduces anesthetic costs significantly as compared to other high volume machines. The study will compare the a low-flow anesthesia machine to a traditional anesthesia machine during routine elective general surgery in patients with ASA ratings of 1-2 under general anesthesia receiving standard care.
Eligibility Criteria
Inclusion Criteria
- Age 18-65 years
- Undergo surgery under general anesthesia in UCI Medical Center
- Agree to sign the consent and HIPAA forms
- Subjects who are able to receive sevoflurane
Exclusion Criteria
- Subjects under the age of 18
- Chronic Obstructive Pulmonary Disease (COPD)
- Body Mass Index (BMI) > 30
- ASA > 2
- Pregnant females
- Procedures less than 2 hours
- Those with known sensitivity to sevoflurane or other halogenated agents; those with known or suspected susceptibility to malignant hyperthermia
- Severe Cardiovascular Disease: Left Ventricular Ejection Fraction (LVEF) < 30%
Data sourced from ClinicalTrials.gov (NCT04851314). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.