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Phase 2 N=161 Randomized Triple-blind Prevention

Pre-operative Tamsulosin and Time to Spontaneous Void After Hysterectomy

Urinary Retention Postoperative

Enrolled (actual)
161
Serious AEs
1.9%
Results posted
Feb 2024
Primary outcome: Primary: Time to Spontaneous Void — 1.63; 1.42 hours

Study Design & Population

Study type
Interventional
Phase
Phase 2
Interventions
Tamsulosin (Drug); Placebo (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
Female
Sponsor
University of Arizona
Primary completion
Jun 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Time to Spontaneous Void
1.63; 1.42
SECONDARY
Time to Discharge From the Post-anesthesia Care Unit
2.4; 2.6

Summary

The aim of this study is to determine if a one time dose of tamsulosin given pre-operatively decreases the time to void and the time to discharge after minimally invasive hysterectomy.

Eligibility Criteria

Inclusion Criteria

  • Women 18-80 undergoing outpatient minimally invasive hysterectomy

Exclusion Criteria

  • Inability to provide informed consent
  • Bladder malignancy
  • Intra-operative bladder or ureteral injury; anticipated prolonged bladder catheterization
  • Plan for sling or anterior repair
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04859660). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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