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N/A N=389

A Retrospective Review of Rib Fracture Pain Management at a London Major Trauma Centre

Rib Fractures · Pain, Acute

Enrolled (actual)
389
Serious AEs
62.2%
Results posted
Nov 2024
Primary outcome: Primary: The Proportion of Patients With a Reduction in Pain — 101; 6; 15 Participants

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Regional Anaesthesia (Procedure)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Imperial College Healthcare NHS Trust
Primary completion
Mar 2021

Outcome Measures

OutcomeResultp-value
PRIMARY
The Proportion of Patients With a Reduction in Pain
101; 6; 15
SECONDARY
Opioid Consumption (mg/24h)
0; 15; 10
SECONDARY
Nausea and Vomiting
117; 10; 2
SECONDARY
Number of Patients With Respiratory Complication(s)'
110; 10; 13
SECONDARY
Intensive Care Admission
30; 1; 2
SECONDARY
Intensive Care Admission
30; 1; 2
SECONDARY
Number of Days of Mechanical Ventilation
0; 0; 0

Summary

Thoracic epidural analgesia (TEA) is widely considered to be the current gold standard treatment for rib fracture pain and is used in the Imperial invasive treatment pathway for rib fractures. However, TEA are often contraindicated due to other injuries or the use of anticoagulant medications, which also contraindicates other invasive nerve block techniques e.g. paravertebral catheters. A number of case reports have reported the safe use of alternative techniques such as Serratus Anterior Blocks (SAPB) and Erector Spinae Blocks (ESPB) and the anaesthesia community has taken them up widely based on this relatively limited evidence. In view of this, Womack et al recently published a large retrospective review examining the safety and efficacy of ultrasound guided paravertebral catheter analgesia techniques in rib fracture management along with small numbers of ESPBs. However, this data did not report the analgesic efficacy, patient reported pain relief or respiratory complications.The goal is to advance this body of evidence by reviewing our larger data set concerning the use of TEA and alternative regional techniques such as ESPB and SAPB. This comprehensive review will benefit patients by documenting the efficacy and safety of these techniques for clinicians managing rib fracture patients.

Eligibility Criteria

Inclusion Criteria

  • Patients aged > 18 years of age presenting with traumatic rib fractures in a major trauma centre over the past 5 years
  • Meet the criteria for the Imperial College Healthcare NHS Trust 'Invasive rib fracture management pathway'

Exclusion Criteria

  • Under 18 years old
  • Prisoners
  • Pregnant
  • Private patients
  • Meet the criteria for the Imperial College Healthcare NHS Trust 'Non-invasive rib fracture management pathway'
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04863807). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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