N/A N=58 Randomized Single-blind Treatment

Gaining Optimism After Weight Loss Surgery (GOALS) II

Bariatric Surgery

Bottom Line

View on ClinicalTrials.gov: NCT04868032 ↗

Enrolled (actual)

Serious AEs

3.5%

Results posted

Mar 2026

Primary outcome: Primary: Number of Intervention Sessions Completed — 9.6 Sessions completed

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Positive Psychology-Motivational Interviewing (Behavioral); Physical Activity Education Control (Behavioral)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Massachusetts General Hospital
Primary completion: Feb 2025

Outcome Measures

Outcome	Result	p-value
PRIMARY Number of Intervention Sessions Completed	9.6	—
PRIMARY Intervention Acceptability	8.5; 8.9; 8.6; 9.0	—
SECONDARY Change in Moderate to Vigorous Physical Activity (MVPA)	109.47; 110.33; 113.05; 103.46; 125.75; 93.09	—
SECONDARY Change in Steps	5180.53; 4782.07; 5219.74; 4849.27; 5306.91; 4572.32	—
SECONDARY Change in Light Physical Activity	253.28; 230.44; 253.86; 232.11; 245.69; 234.66	—
SECONDARY Change in Positive Affect	34.90; 28.28; 38.38; 30.96; 36.27; 32.15	—
SECONDARY Change in Optimism	10.28; 11.59; 10.07; 11.73; 10.69; 11.24	—
SECONDARY Change in Depressive Symptoms	3.34; 5.14; 2.67; 4.19; 3.42; 4.08	—
SECONDARY Change in Anxiety	6.38; 8; 5.56; 7.77; 5.04; 7.32	—
SECONDARY Change in Exercise Identity	30.83; 25.03; 41.04; 30.69; 38.19; 28.04	—
SECONDARY Change in General Self-Efficacy	32.55; 31.76; 34.00; 32.00; 33.65; 31.52	—
SECONDARY Change in Exercise-specific Self-efficacy	46.52; 45.63; 57.56; 37.00; 50.08; 36.96	—
SECONDARY Change in Internalized Weight Bias	3.33; 3.56; 2.89; 3.33; 2.58; 3.13	—
SECONDARY Change in Bariatric Surgery-specific Diet and Vitamin Adherence	44.59; 41.90; 49.44; 42.00; 47.96; 41.04	—
SECONDARY Change in Self-Reported Physical Activity	1341.31; 771.83; 1719.82; 1424.11; 2358.94; 1309.01	—
SECONDARY Change in Body Mass Index	35.68; 36.46; 34.40; 36.11; 33.652; 35.91	—
SECONDARY Change in Systolic Blood Pressure (Millimeters of Mercury)	121.24; 116.55; 123.20; 119.21; 121.75; 120.64	—
SECONDARY Change in Aerobic Capacity and Endurance	477.20; 482.39; 515.24; 507.68; 511.41; 500.72	—
SECONDARY Change in Body Composition	47.90; 46.4; 44.97; 44.75; 45.22; 45.28	—
SECONDARY Change in A1C	5.45; 5.19; 5.43; 5.27; 5.38; 5.36	—
SECONDARY Change in HDL Cholesterol	53.62; 52.28; 57.88; 56.30; 62.87; 57.88	—
SECONDARY Change in Inflammation	4.11; 3.80; 2.71; 2.55; 3.07; 2.86	—
SECONDARY Change in Physical Activity Enjoyment	83.38; 83; 96.85; 89.21; 89.69; 82.76	—
SECONDARY Change in Diastolic Blood Pressure (Millimeters of Mercury)	69.00; 66.59; 69.12; 71.58; 70.04; 70.84	—
SECONDARY Change in LDL Cholesterol	105.28; 92.63; 103.96; 97.39; 104.96; 89.48	—
SECONDARY Change in Triglycerides	102.93; 124.28; 102.72; 113.61; 91.13; 109.36	—

Summary

This randomized controlled trial examines the feasibility, acceptability, and preliminary impact of an adapted positive psychology-motivational interviewing (PP-MI) intervention for physical activity among patients who have recently undergone bariatric surgery compared to an enhanced usual care control.

Eligibility Criteria

Inclusion Criteria

Adult (age 18+)
History of bariatric surgery (gastric bypass or sleeve gastrectomy) at one of two academic medical centers within the past 6-12 months
Interest in increasing physical activity
Low physical activity, defined as <200 minutes/week self-reported moderate- to-vigorous physical activity
Access to telephone for study sessions
Able to read and speak English

Exclusion Criteria

Cognitive deficits precluding participation or informed consent
Illness likely to lead to death in the next 6 months
Inability to be physically active (e.g., severe arthritis)
Participation in another program targeting physical activity besides their standard offerings at the surgery center.
Severe psychiatric condition limiting ability to participate (e.g., psychosis, active substance use disorder)

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04868032). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.