N/A
N=141
Guided Self-help for Common Mental Disorders
Bibliotherapy
Bottom Line
View on ClinicalTrials.gov: NCT04870099 ↗Enrolled (actual)
141
Serious AEs
0.0%
Results posted
Jul 2023
Primary outcome: Primary: 6-week Change in Kessler 6 Psychological Distress Scale (K6) — -5.68 score on a scale (K6)
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Doing What Matters in Times of Stress: An Illustrated Guide (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Indiana University
- Primary completion
- Feb 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY 6-week Change in Kessler 6 Psychological Distress Scale (K6) |
-5.68 | — |
| PRIMARY 6-week Change in the WHO 5 Well-being Index (WHO-5) |
13.61 | — |
| SECONDARY 6-week Change in Emotion Regulation Scale (ERQ) - Reappraisal Subscale |
0.89 | — |
| SECONDARY 6-week Change in the Emotion Regulation Scale (ERQ) - Suppression Subscale |
-0.46 | — |
| SECONDARY 3-month Change in Kessler 6 Psychological Distress Scale (K6; 0 - 24) |
-4.91 | — |
| SECONDARY 3-month Change in the WHO 5 Well-being Index (WHO-5) |
15.95 | — |
Summary
Common mental disorders (CMDs) like depression and anxiety account for a large proportion of disability worldwide. Access to effective treatments like cognitive-behavioral therapy (CBT) is limited and has not reduced the public health burden of psychopathology. For patients with mild-moderate CMDs, lower-intensity treatments like guided self-help CBT (GSH-CBT) are effective and more scalable (e.g., via the internet). The advent of social media has opened avenues for dissemination of GSH-CBTs and allows for passive sensing of mood, thinking, behavior, and social networks. We propose to leverage a social media platform used by over a fifth of the United States (Twitter) as a recruitment tool to virtually screen over 150 individuals, recruit N=60 to a 5-week course of GSH-CBT, and extract social media data from individuals engaged in GSH-CBT. Sociodemographic and social media data will be used to predict engagement, outcomes, and processes in GSH-CBT.
Eligibility Criteria
Inclusion Criteria
- At least mild distress: K6 score ≥ 6
- Having reasonably regular access to the internet or a telephone
Exclusion Criteria
- Suicidality: Patient Health Questionnaire-9 (PHQ9) item 9 ("thoughts that you would be better off dead, or of hurting yourself ") ≥ 2 ("more than half the days")
Data sourced from ClinicalTrials.gov (NCT04870099). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.