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N/A N=186

Immunity to Serotype 19A Streptococcus Pneumoniae in Children Vaccinated With PCV10

Pneumococcal Infections

Enrolled (actual)
186
Serious AEs
0.0%
Results posted
Aug 2021
Primary outcome: Primary: Persistence of Humoral Immunity Following PCV10 Vaccination — 0.32; 0.35 micrograms per ml

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
10-valent pneumococcal conjugate vaccine, PCV10 (Biological)
Age
Pediatric · 0+ yrs
Sex
All
Sponsor
Finnish Institute for Health and Welfare
Primary completion
May 2013

Outcome Measures

OutcomeResultp-value
PRIMARY
Persistence of Humoral Immunity Following PCV10 Vaccination
0.32; 0.35

Summary

The aim of the study are to assess the persistence of immunity against vaccine serotypes (VSTs) and vaccine-related serotypes in PCV10 vaccinated children in Finland.

Eligibility Criteria

Inclusion Criteria

  • Completed PCV10 vaccination with 3 or 4 doses (2+1 or 3+1 schedule) before blood sampling at age of 13 months
  • Age at sample collection 13 months, 2 years or 3 years
  • PCV10 vaccination received 2-6 weeks before sample collection at the age of 1 year
  • Informed consent obtained covering the planned analyses

Exclusion Criteria

  • PCV13 or PPV23 dose received
  • Informed consent withdrawn
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04912297). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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