N/A
Completed N=160
Success Rate of 4 Injection Protocols for Mandibular First Molars With Symptomatic Irreversible Pulpitis
Source: ClinicalTrials.gov NCT04929522 ↗Enrolled (actual)
160
Serious AEs
0.0%
Results posted
Oct 2021
Primary outcomePrimary: Number of Participants With Successful Injection Technique Assessed by Verbal Rating Scale (VRS) — 16; 37; 29; 26 Participants
Summary
Achieving profound anesthesia during endodontic treatment of mandibular molars with symptomatic irreversible pulpitis is still a demanding clinical challenge. therefore, the success Rate of 4 Injection protocols for Mandibular First Molars with Symptomatic Irreversible Pulpitis was evaluated clinically in a randomized triple-blind trial
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Successful Injection Technique Assessed by Verbal Rating Scale (VRS) |
16; 37; 29; 26 | — |
| SECONDARY Changes in the Heart Rate Before, During and After the Injection |
72; 72; 71; 71; 71; 72 | — |
Eligibility Criteria
Inclusion Criteria
- Patients included in the study were healthy males and females
- (Category: American Society of Anesthesiologists class 1)
- aged 21-49 years
- with no physical disability, facial paresthesia or psychological problems
- presenting with a single vital mature mandibular first molar, with signs and/or symptoms of symptomatic irreversible pulpitis
Exclusion Criteria
- Pregnant women
- patients who took analgesics or other medications that would alter the inflammatory response of the pulp or provide analgesia 6- hours pre-operatively
- those with known sensitivity to the pharmaceuticals used in this trial.
- those with pathological periodontal pockets
Data sourced from ClinicalTrials.gov (NCT04929522). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.