N/A
Completed N=66
Walking Exercise on Memory, Subjective Cognitive Complaint, and Brain-derived Neurotrophic Factor for Hypertension
Source: ClinicalTrials.gov NCT04930263 ↗Enrolled (actual)
66
Serious AEs
0.0%
Results posted
Dec 2021
Primary outcomePrimary: Memory Function — 25.5; 24.0; 9.7; 9.0 score on a scale
Summary
The purpose of this study is to determine the effect of 6-month aerobic walking program on memory, subjective cognitive complaints, and brain-derived neurotrophic factor for older hypertensive women. Participants will be randomly assigned to the experimental group and the control group. The intervention group will last for 24 weeks. The outcome measurements included memory, subjective cognitive complaints, and brain-derived neurotrophic factor.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Memory Function |
25.5; 24.0; 9.7; 9.0 | — |
| SECONDARY Brain-derived Neurotrophic Factor |
206.0; 176.2 | — |
| SECONDARY Subjective Cognitive Complaints |
18.9; 20.5 | — |
Eligibility Criteria
Inclusion Criteria
- aged 60-80 years old,
- a diagnosed of hypertension ≥ 6 months
- self-reporting the signs of memory or thinking skills problems
Exclusion Criteria
- probable cognitive impairment as assessed by Montreal Cognitive Assessment ( < 24 points),
- significant conditions limiting walking ability (e.g. musculoskeletal problems, visual impairment, etc.),
- already participating in 30 minutes or more of moderate-intensity exercise five times a week
- a history of severe cardiovascular disease,
- a history of neurologic or psychiatric disorder such as stroke, head injury dementia, Parkinson disease, and depression.
Data sourced from ClinicalTrials.gov (NCT04930263). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.