N/A
N=39
Prevention and Early Identification for High Risk Youth in School-based Clinics
Community Mental Health Services · Adolescent Well Being · Resilience, Psychological · Health Equity · Screening
Bottom Line
View on ClinicalTrials.gov: NCT04935710 ↗Enrolled (actual)
39
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcome: Primary: Kiddie Computerized Adaptive Testing Self Report (K-CAT-S) — 45.08; 39.45; 36.24; 41.3 Score on a scale — p=0.37
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- COPE2Thrive (Behavioral); Usual care (Other)
- Age
- Pediatric, Adult · 12+ yrs
- Sex
- All
- Sponsor
- Cambridge Health Alliance
- Primary completion
- Feb 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Kiddie Computerized Adaptive Testing Self Report (K-CAT-S) |
45.08; 39.45; 36.24; 41.3; 41.8; 34.4 | 0.37 |
| PRIMARY Weiss Functional Impairment Rating Scale - Self Report (WFIRS-S) |
0.08; 0.10; 0.06; 0.03; 0.06; 0.03 | 0.001 sig |
| SECONDARY Kiddie Computerized Adaptive Testing Parent Report(K-CAT-P) |
29.74; 11.98; 27.56; 21.57; 22.01; 8.72 | 0.04 sig |
| SECONDARY Weiss Functional Impairment Rating Scale - Parent Report (WFIRS-P) |
0.44; 0.10; 0.69; 0.83; 0.21; 0.1 | — |
Summary
The proposed research project provides a novel approach to screening, early assessment, and preventive interventions for high-risk youth in racial/ethnic/linguistically (REL)-diverse communities.
* The investigators assess a health promotion intervention as a way of reducing treatment disparities in REL-minority youth. This population is underrepresented in child psychiatry research. It is often excluded from clinical trials of medication or therapy because of challenges with transportation, literacy, resources, or other issues.
* The study will take place during or following a healthcare crisis and economic recession, making findings relevant to understanding the mechanisms by which hardship translates into youth mental illness.
* The innovative integration of online screening into school-based clinics and community-based settings in REL-minority communities is made possible by the combination of access to a new technology (CAT) in the context of a learning health community serving a REL-minority population.
* Empirical research on the impact of a resilience-based prevention intervention in youth and youth at risk is both innovative and much needed during this period of health, social and economic crisis.
Eligibility Criteria
- High school students in CHA's catchment area (Cambridge, Chelsea, Everett, Malden, Revere, Somerville, Winthrop)
- Youth who are fluent in English, Haitian Creole, Portuguese, or Spanish.
- Youth who experience at least some symptoms, defined as a K-CAT-S score (from Aim 1) of moderate on at least one diagnosis with at least mild functional impairment. Patients with more severe symptoms or functional impairment or who do not meet the exclusion criteria are also eligible.
Inclusion Criteria for COPE2Thrive:
- High school students in CHA's catchment area (Cambridge, Chelsea, Everett, Malden, Revere, Somerville, Winthrop)
- Youth who are fluent in English, Haitian-Creole, Portuguese, or Spanish.
- Youth who have completed WFIRS and K-CAT, and who do not meet the exclusion criteria.
Exclusion Criteria
- 12th-graders will be excluded from the COPE2Thrive program since the participants will not be available for the study's duration.
- Students who are already receiving behavioral health care.
- Students who are considered to be seriously suicidal and in need of urgent care, in which case the participants would be ineligible based on the fact that the participants will be receiving behavioral health care.
Data sourced from ClinicalTrials.gov (NCT04935710). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.