N/A Completed N=20 Randomized Double-blind Treatment

Intra-articular Injection in Arthroscopic Management of Temporomandibular Diseases

Temporomandibular Joint Disorders

Source: ClinicalTrials.gov NCT04936945 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Sep 2024

Primary outcomePrimary: Maximum Interincisal Opening (MIO) Measurements — 23.1; 27.9; 33.8; 35.6 Millimeter

Summary

The aim of this study is to evaluate the efficacy of intra-articular injection of platelet rich plasma versus hyaluronic acid following diagnostic arthroscopy in the management of patients suffering from degenerative temporomandibular joint (TMJ). This is a prospective randomized study of 20 patients with TMJ degenerative joint diseases Wilkes IV, V. Patients will be divided into two groups; Group A: will be treated with operative arthroscopy plus intra-articular platelet rich plasma. Group B: will be treated with operative arthroscopy plus intra-articular hyaluronic acid.

Outcome Measures

Outcome	Result	p-value
PRIMARY Maximum Interincisal Opening (MIO) Measurements	23.1; 27.9; 33.8; 35.6; 36; 36.7	—
PRIMARY Pain Intensity Measurements	49; 49; 28; 30; 21; 25	—

Eligibility Criteria

Inclusion Criteria

- All patients with reduced mouth opening and/or painful maximum mouth opening.
Joint pain.
Patients with radiological evidence of degenerative joint disease.
Patients with unsuccessful medical conservative treatment for at least two months.
Unilateral or bilateral temporomandibular joint involvement.
Wilkes stages IV and V

Exclusion Criteria

- Patients with bony ankylosis .
Patients with advanced resorption of the glenoid fossa.
Patients with infection or tumors around joint area
Patients unfit for intervention medically.
Patients who refused to share in the study

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04936945). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.