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N/A Completed N=8 Randomized Prevention

High Intensity Interval Exercise SCI

Spinal Cord Injuries · cardiometabolic disease
Source: ClinicalTrials.gov NCT04940598 ↗
Enrolled (actual)
8
Serious AEs
0.0%
Results posted
Jul 2024
Primary outcomePrimary: Aerobic Capacity Baseline — 11.6; 10 ml/kg/min

Summary

This study will determine if the implementation of a home-based telehealth high intensity interval exercise-training (HIIT)program can significantly improve cardiometabolic health and physical function in a cohort of individuals with longstanding spinal cord injury (SCI). Results from this study will determine feasibility, overall enjoyment, and health impact of implementing a home-based telehealth HIIT program in individuals with SCI.

Outcome Measures

OutcomeResultp-value
PRIMARY
Aerobic Capacity Baseline
11.6; 10
PRIMARY
Aerobic Capacity Week 16
13.6; 9.9
PRIMARY
Matsuda Index Baseline
3.5; 6.1
PRIMARY
Matsuda Index Week 16
5.3; 6.5
PRIMARY
Cholesterol Baseline
179.2; 178
PRIMARY
Cholesterol Week 16
193.8; 188
PRIMARY
Body Composition Baseline
42.4; 47.5
PRIMARY
Body Composition Week 16
41.9; 46.9
PRIMARY
Triglycerides Baseline
132.6; 126.3
PRIMARY
Triglycerides Week 16
122.8; 102.3
PRIMARY
HDL Baseline
45.6; 51.7
PRIMARY
HDL Week 16
52; 57.7
PRIMARY
LDL Baseline
107.1; 101.1
PRIMARY
LDL Week 16
117.5; 109.7

Eligibility Criteria

Inclusion Criteria

  • Men and women, 19-65 years of age.
  • Confirmed diagnosis of traumatic SCI at the cervical or thoracic level (C7-T12), classified as A, B, C, or D (motor and sensory complete or incomplete) on the AIS scale.
  • At least 6 months post-injury.
  • Able to independently operate an arm ergometer.
  • Have access to a wireless internet connection.
  • Medically stable, able to provide informed consent.

Exclusion Criteria

  • Cardiovascular or renal diseases.
  • Pregnant women
  • Orthopedic conditions that prevents arm ergomtery
  • Upper extremity musculoskeletal conditions that prevents arm ergometry.
  • Neurological disorder that prevents arm ergometry
  • Participation in a structured exercise program currently or in the past 3 months.
  • Unable to perform exercise interventions

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View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04940598). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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