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N/A N=30 Randomized Treatment

Acupuncture Therapy for COVID-Related Olfactory Loss

Olfactory Dysfunction · COVID-19

Enrolled (actual)
30
Serious AEs
0.0%
Results posted
Mar 2024
Primary outcome: Primary: Change in University of Pennsylvania Smell Identification Test (UPSIT) Scores — 2.571; 3.182 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Acupuncture Therapy (Device); Budesonide (Drug); Olfactory Training (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Mayo Clinic
Primary completion
Apr 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in University of Pennsylvania Smell Identification Test (UPSIT) Scores
2.571; 3.182
SECONDARY
Change in Patient-reported Subjective Olfactory Loss
1.857; 1.727
SECONDARY
Change in Sino-Nasal Outcome Test (SNOT-22)
7.143; 3.455

Summary

This study is looking at the role of acupuncture as a treatment for olfactory dysfunction in patients who tested positive for COVID-19.

Eligibility Criteria

Inclusion Criteria

  • 18 years or older.
  • Patients with post-viral olfactory dysfunction > 4 weeks.
  • History of positive COVID-19 PCR.

Exclusion Criteria

  • Less than 18 years of age.
  • Active sinus infection.
  • New diagnosis of untreated CRS.
  • Prior diagnosis of dementia or Parkinson's disease.
  • Prior head trauma or neurosurgical procedure resulting in olfactory loss.
  • Patients who do not speak or read English.
  • Patients unable to understand and sign the study consent.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04952389). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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