N/A
Completed N=25
Changes to Function and Quality of Life and Patient Experience for Patients Undergoing Treatments for Recurrent Oropharyngeal Cancer
Recurrent Oropharynx Carcinoma
Source: ClinicalTrials.gov NCT04952922 ↗
Enrolled (actual)
25
Serious AEs
—
Results posted
Aug 2025
Primary outcomePrimary: Patient Reported Swallowing Related Quality of Life — 50; 40; 40 score on a scale
Summary
The purpose of this research project is to measure changes in communication, swallowing and quality of life and individual patient priorities which may happen over time in patients with a diagnosis of recurrent head and neck cancer, specifically recurrent cancer (cancer which has returned after previous treatment) of the back of the throat, the tonsils and/or the base of tongue (recurrent oropharyngeal cancer) and what it is like for patients and their significant others to experience these changes over time.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Patient Reported Swallowing Related Quality of Life |
50; 40; 40 | — |
| SECONDARY Swallowing Status Measured Using the 100ml Water Swallow Test |
9.7; 16.6; 17.9 | — |
| SECONDARY Swallowing Status Measured With the Standardisation Initiative Functional Diet Scale (IDDSI-FDS) |
7; 6; 6 | — |
Eligibility Criteria
Inclusion Criteria
- Adult (aged 18 years or over) competent to provide consent
- Have a diagnosis of recurrent OPC
- Have adequate linguistic and cognitive function to participate in interview
- English speaking
Exclusion Criteria
- Any previous medical condition, other than HNC, which has a known impact on communication/ swallowing (Parkinson's Disease, Multiple Sclerosis, cerebral vascular accident (CVA)
Data sourced from ClinicalTrials.gov (NCT04952922). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.