N/A
N=25
Changes to Function and Quality of Life and Patient Experience for Patients Undergoing Treatments for Recurrent Oropharyngeal Cancer
Recurrent Oropharynx Carcinoma
Bottom Line
View on ClinicalTrials.gov: NCT04952922 ↗Enrolled (actual)
25
Serious AEs
—
Results posted
Aug 2025
Primary outcome: Primary: Patient Reported Swallowing Related Quality of Life — 50; 40; 40 score on a scale
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Treatment for recurrent oropharyngeal cancer (curative/ palliative) (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Royal Marsden NHS Foundation Trust
- Primary completion
- May 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Patient Reported Swallowing Related Quality of Life |
50; 40; 40 | — |
| SECONDARY Swallowing Status Measured Using the 100ml Water Swallow Test |
9.7; 16.6; 17.9 | — |
| SECONDARY Swallowing Status Measured With the Standardisation Initiative Functional Diet Scale (IDDSI-FDS) |
7; 6; 6 | — |
Summary
The purpose of this research project is to measure changes in communication, swallowing and quality of life and individual patient priorities which may happen over time in patients with a diagnosis of recurrent head and neck cancer, specifically recurrent cancer (cancer which has returned after previous treatment) of the back of the throat, the tonsils and/or the base of tongue (recurrent oropharyngeal cancer) and what it is like for patients and their significant others to experience these changes over time.
Eligibility Criteria
Inclusion Criteria
- Adult (aged 18 years or over) competent to provide consent
- Have a diagnosis of recurrent OPC
- Have adequate linguistic and cognitive function to participate in interview
- English speaking
Exclusion Criteria
- Any previous medical condition, other than HNC, which has a known impact on communication/ swallowing (Parkinson's Disease, Multiple Sclerosis, cerebral vascular accident (CVA)
Data sourced from ClinicalTrials.gov (NCT04952922). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.