N/A
N=1,132
Correcting Public Misperceptions About Very Low Nicotine Content Cigarettes
Tobacco Use, Cigarette Use
Bottom Line
View on ClinicalTrials.gov: NCT04974489 ↗Enrolled (actual)
1,132
Serious AEs
—
Results posted
Nov 2022
Primary outcome: Primary: Very Low Nicotine Content (VLNC) Misperception — 3.12; 3.04; 3.04; 3.36 score on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Emotion-based messages about the harm of VLNC (Behavioral); Continued-harm-framed messages about the harm of VLNC (Behavioral); Myth-refuting messages about the harm of VLNC (Behavioral); Control messages about littering (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
- Primary completion
- Aug 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Very Low Nicotine Content (VLNC) Misperception |
3.12; 3.04; 3.04; 3.36 | — |
| PRIMARY Percentage of Participants With Very Low Nicotine Content (VLNC) Misperception About Harm (Dichotomized) |
18.3; 12.6; 11.4; 38.2 | — |
| PRIMARY Percentage of Participants With Very Low Nicotine Content (VLNC) Misperception About Cancer (Dichotomized) |
16.8; 11.1; 9.5; 31.8 | — |
| PRIMARY Percentage of Participants With Very Low Nicotine Content (VLNC) Misperception About Death (Dichotomized) |
16.4; 16.1; 9.9; 34.5 | — |
| SECONDARY Quit Intentions |
2.88; 2.80; 2.87; 2.85 | — |
Summary
Tobacco use is the leading preventable cause of cancer and cancer deaths in the US. While most (69%) smokers want to quit, only 6% succeed in doing so each year. For many smokers, the addictiveness of nicotine makes quitting very difficult. To reduce cigarette smoking and resulting harms, FDA has announced a comprehensive approach to tobacco and nicotine regulation that includes moving toward a very low nicotine content (VLNC) standard for cigarettes. Greatly reduced nicotine levels would facilitate smoking cessation. However, the maximal success of the policy may require public understanding that, although these new cigarettes are less addictive, their high toxicity and carcinogenicity are unchanged. Yet, nearly half of adult smokers incorrectly think smoking VLNC cigarettes is less harmful than smoking current cigarettes (the VLNC misperception). Additionally, 24% of smokers said they would be less likely to quit if a VLNC regulation is enacted. Thus, the VLNC misperception may partially undermine a nicotine reduction policy. Although communication research suggests it is challenging to change people's incorrect understanding, new communication techniques may help reduce the VLNC misperception. In this randomized trial we will examine whether messages about the harm of VLNC cigarettes can reduce the VLNC misperception and increase intention to quit in a nicotine reduction scenario.
Eligibility Criteria
Inclusion Criteria
- Current Cigarette Smoker
- Age 18 or older
- Enrolled in existing nationally representative panel where recruitment is based
Exclusion Criteria
- None
Data sourced from ClinicalTrials.gov (NCT04974489). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.