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N/A N=1,132 Randomized Prevention

Correcting Public Misperceptions About Very Low Nicotine Content Cigarettes

Tobacco Use, Cigarette Use

Enrolled (actual)
1,132
Serious AEs
Results posted
Nov 2022
Primary outcome: Primary: Very Low Nicotine Content (VLNC) Misperception — 3.12; 3.04; 3.04; 3.36 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Emotion-based messages about the harm of VLNC (Behavioral); Continued-harm-framed messages about the harm of VLNC (Behavioral); Myth-refuting messages about the harm of VLNC (Behavioral); Control messages about littering (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
UNC Lineberger Comprehensive Cancer Center
Primary completion
Aug 2021

Outcome Measures

OutcomeResultp-value
PRIMARY
Very Low Nicotine Content (VLNC) Misperception
3.12; 3.04; 3.04; 3.36
PRIMARY
Percentage of Participants With Very Low Nicotine Content (VLNC) Misperception About Harm (Dichotomized)
18.3; 12.6; 11.4; 38.2
PRIMARY
Percentage of Participants With Very Low Nicotine Content (VLNC) Misperception About Cancer (Dichotomized)
16.8; 11.1; 9.5; 31.8
PRIMARY
Percentage of Participants With Very Low Nicotine Content (VLNC) Misperception About Death (Dichotomized)
16.4; 16.1; 9.9; 34.5
SECONDARY
Quit Intentions
2.88; 2.80; 2.87; 2.85

Summary

Tobacco use is the leading preventable cause of cancer and cancer deaths in the US. While most (69%) smokers want to quit, only 6% succeed in doing so each year. For many smokers, the addictiveness of nicotine makes quitting very difficult. To reduce cigarette smoking and resulting harms, FDA has announced a comprehensive approach to tobacco and nicotine regulation that includes moving toward a very low nicotine content (VLNC) standard for cigarettes. Greatly reduced nicotine levels would facilitate smoking cessation. However, the maximal success of the policy may require public understanding that, although these new cigarettes are less addictive, their high toxicity and carcinogenicity are unchanged. Yet, nearly half of adult smokers incorrectly think smoking VLNC cigarettes is less harmful than smoking current cigarettes (the VLNC misperception). Additionally, 24% of smokers said they would be less likely to quit if a VLNC regulation is enacted. Thus, the VLNC misperception may partially undermine a nicotine reduction policy. Although communication research suggests it is challenging to change people's incorrect understanding, new communication techniques may help reduce the VLNC misperception. In this randomized trial we will examine whether messages about the harm of VLNC cigarettes can reduce the VLNC misperception and increase intention to quit in a nicotine reduction scenario.

Eligibility Criteria

Inclusion Criteria

  • Current Cigarette Smoker
  • Age 18 or older
  • Enrolled in existing nationally representative panel where recruitment is based

Exclusion Criteria

  • None
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT04974489). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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