N/A
N=49,210
Leveraging Electronic Health Record (EHR) Tools to Reduce Health Disparities for Patients With Uncontrolled Hypertension
Hypertension · Blood Pressure
Bottom Line
View on ClinicalTrials.gov: NCT05030467 ↗Enrolled (actual)
49,210
Serious AEs
0.1%
Results posted
Jun 2025
Primary outcome: Primary: Change in Systolic Blood Pressure — -11.0; -11.0 mmHg
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- REDUCE-BP Intervention (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Brigham and Women's Hospital
- Primary completion
- May 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Systolic Blood Pressure |
-11.0; -11.0 | — |
| SECONDARY Percentage of Patients With Well-controlled Blood Pressure |
16910; 16441 | 0.011 sig |
| SECONDARY Percentage of Patients With Intensification of Medication |
— | — |
| SECONDARY Percentage of Patients With Guideline-concordant Medications |
— | — |
| SECONDARY Change in Diastolic Blood Pressure |
-4.4; -4.3 | 0.383 |
| SECONDARY Systolic Blood Pressure Differences |
— | — |
Summary
A two-arm cluster randomized controlled trial targeting primary care providers will be conducted to evaluate the impact of a multicomponent electronic health record (EHR) intervention on hypertension management. Given the cluster trial design, randomization will be conducted at the site level, and in the intervention sites, all eligible providers will receive the intervention. The intervention consists of enhancing tools already available to primary care providers in the EHR system, including developing and implementing provider disparities dashboards, enhancing electronic decision support, and simplifying self-monitoring orders and communication materials. The intervention aims to improve blood pressure control and reduce health disparities in racial and ethnic minorities. Findings from this trial will provide important insight into whether a multicomponent intervention targeting providers and leveraging health information technology can reduce health disparities.
Eligibility Criteria
24 practices will be randomized to either Intervention or Control. We will include in the analysis patients who meet the following Inclusion Criteria:
- Medical Group Medical Home Population: 1 visit with Primary Care Physician (PCP) in past 2 years (rolling 24 months) and Patient has a medical group PCP as their EPIC General PCP
- Current age 18-85 years
- Hypertension diagnosis on EPIC Problem list OR at least 2 visits (office/telehealth/telephonic) with an encounter diagnosis of hypertension on different dates, with any during the last 24 months (rolling dates) performing provider
- Latest outpatient/ambulatory (exclude urgent care) systolic blood pressure ≥140 or diastolic blood pressure ≥90 (12 months rolling) (lowest measure if more than one taken at the same time)
Exclusion Criteria
- Patients not meeting the inclusion criteria above will not be included in the analysis of the study. No other exclusion criteria will be used.
Among these eligible patients, patients included in the primary analysis will be those that had an in-person visit at one of the trial clinics.
Data sourced from ClinicalTrials.gov (NCT05030467). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.