N/A
N=40
Weight Loss Intervention for the Reduction of Cancer Risk and Health Disparities in Rural Ohio
Obesity-Related Malignant Neoplasm
Bottom Line
View on ClinicalTrials.gov: NCT05040152 ↗Enrolled (actual)
40
Serious AEs
0.0%
Results posted
Jun 2025
Primary outcome: Primary: Feasibility of a 15-week Telephone-based Weight Loss Intervention — 22; 11 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Dietary Counseling and Surveillance (Behavioral); Exercise Intervention (Other); Informational Intervention (Other); Questionnaire Administration (Other); Telephone-Based Intervention (Behavioral)
- Age
- Adult · 20+ yrs
- Sex
- All
- Sponsor
- Ohio State University Comprehensive Cancer Center
- Primary completion
- May 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Feasibility of a 15-week Telephone-based Weight Loss Intervention |
22; 11 | — |
| SECONDARY Changes in Body Weight (KG) |
-4.93; -2.09 | — |
| SECONDARY Changes in Body Fat Mass |
0.23; 0.11 | — |
Summary
This study determines the feasibility of a telephone-based weight lost intervention in reducing cancer risk and health disparities in rural Ohio. Obesity is the leading preventable cause of cancer, and obesity-related inflammation is linked to elevated cancer risk, independent of obesity itself. Rural populations are a vulnerable population in need of increased access to tailored strategies and benefit from weight loss interventions. This study aims to see whether a telephone-based intervention may help obese people in rural area to reduce body weight, so as to prevent obesity-related cancer.
Eligibility Criteria
Inclusion Criteria
- Body mass index (BMI) >= 25 kg/m^2
- Age: 20-64.9 years
- Not currently participating in any weight loss intervention or meet the physical activity recommendation (150 min/week of moderate-intensity exercise or 75 min/week of vigorous exercise)
- The ability to walk two blocks
- Ability to speak and read English
Exclusion Criteria
- Prior cancer diagnosis (except non-melanoma skin cancer) or severe medical conditions such as unstable cardiovascular disease or digestive disorders that would preclude physical activity and dietary intervention
- Pregnant or nursing women
- Unable to give informed consent
Data sourced from ClinicalTrials.gov (NCT05040152). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.