Phase 2 N=24 Randomized Double-blind Treatment

Therapeutic Effects of Topical Herbal Medicine -Rhubarb Ointment on Rosacea

Rosacea · Chinese Herbal Medicine

Bottom Line

View on ClinicalTrials.gov: NCT05045469 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Apr 2025

Primary outcome: Primary: Reduction of Flushing, Erythema, Telangiectasia, Papules, and Pustules — 1; 1.92 score on a scale

Study Design & Population

Study type: Interventional
Phase: Phase 2
Interventions: dian dao san (Drug)
Age: Adult, Older Adult · 20+ yrs
Sex: All
Sponsor: Chang Gung Memorial Hospital
Primary completion: May 2024

Outcome Measures

Outcome	Result	p-value
PRIMARY Reduction of Flushing, Erythema, Telangiectasia, Papules, and Pustules	1; 1.92	—
SECONDARY Dermatology Quality of Life Index, DQoL	2.83; 6.25	—

Summary

The aim of this study is to investigate the effects of topical herbal medicine in the patients with rosacea.

Eligibility Criteria

Inclusion Criteria

Willing to sign inform consent
Aged above 20 years old with rosacea
No treatment for rosacea within 2 weeks

Exclusion Criteria

With malignant lesion in the rosacea lesion
Rosacea lesion with high risk of infection
Allergy to Chinese herbal medicine patch or ointment
Pregnancy

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05045469). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.