N/A
N=101
Peers and Technology for Adherence, Access, Accountability, and Analytics
Hypertension · Medication Adherence
Bottom Line
View on ClinicalTrials.gov: NCT05051124 ↗Enrolled (actual)
101
Serious AEs
1.0%
Results posted
Mar 2025
Primary outcome: Primary: Absolute Mean Change in Systolic Blood Pressure (SBP) — 11.5 millimeters of mercury (mmHg)
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Peer Delivery of Medications (Behavioral); Health Information Technology (HIT) Platform (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- NYU Langone Health
- Primary completion
- Jan 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Absolute Mean Change in Systolic Blood Pressure (SBP) |
11.5 | — |
| PRIMARY Pill Count Adherence Ratio |
0.99 | — |
| PRIMARY Number of Confirmed Medication Deliveries |
992 | — |
| PRIMARY Number of Peer Completions of HIT Form |
999 | — |
Summary
The overall objective of this project is to utilize the PRECEDE-PROCEED framework to conduct transdisciplinary, translational implementation research focused on improving medication adherence for hypertension control. The central hypothesis is that peer delivery of medications integrated with HIT (PT4A) will be effective in improving hypertension medication adherence, contributing to improved blood pressure among patients with uncontrolled hypertension in western Kenya. This study record will focus on Sub-Aim 2.2: a pilot of the intervention and a survey questionnaire with patients, peers, and clinical staff to evaluate feasibility. The investigators will evaluate impact on systolic blood pressure, medication adherence, and fidelity of implementation. The investigators will also create a retrospective comparator (control) group of CDM patients, through querying AMRS, matched by sex, age, location and initial blood pressure level. The investigators will then use their recorded blood pressure over a comparable period of up to 1 year and to allow for comparison to the blood pressure changes observed in the patients enrolled in the PT4A program to help understand the magnitude and variance of the intervention effects.
Eligibility Criteria
Inclusion Criteria
- Adult patients ≥ 18 years old
- Enrolled in the AMPATH CDM PRogram
- Have uncontrolled hypertension (defined as systolic blood pressures ≥ 140 or diastolic blood pressure ≥ 90)
Exclusion Criteria
- Acute illness requiring immediate medical attention
- Terminal illness
- Inability to provide informed consent
Data sourced from ClinicalTrials.gov (NCT05051124). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.