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N/A N=216 Randomized Single-blind Diagnostic

Crowdsourcing to Reduce HIV Stigma Among Adolescents and Young Adults in Kazakhstan

Stigma, Social · HIV Testing

Enrolled (actual)
216
Serious AEs
0.0%
Results posted
Dec 2024
Primary outcome: Primary: Mean Score Change in Total HIV Stigma Scale — 47.48; 47.89; 44.60; 47.32 units on a scale — p=0.083

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Digital Crowdsourced Intervention to Reduce HIV Stigma among Adolescents and Young Adults (Behavioral)
Age
Pediatric, Adult · 16+ yrs
Sex
All
Sponsor
Columbia University
Primary completion
Aug 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Mean Score Change in Total HIV Stigma Scale
47.48; 47.89; 44.60; 47.32 0.083
SECONDARY
Mean Change in Perceived HIV Test Stigma
5.92; 5.70; 5.19; 5.64 0.032 sig
SECONDARY
Mean Change in Perceived HIV Healthcare Stigma Subscale
5.80; 5.90; 5.57; 5.89 0.48
SECONDARY
Mean Change in Fear & Judgement HIV Stigma Sub-scale
11.12; 11.24; 10.56; 11.08 0.48
SECONDARY
Mean Change in Perceived Community HIV Stigma Subscale
24.65; 25.05; 23.28; 24.74 0.37
SECONDARY
Uptake of HIV Self-test
30; 18 0.099

Summary

This project will assess whether a digital crowdsourced intervention can reduce HIV stigma and promote HIV self-testing among adolescents and young adults (AYA). NIH has emphasized the need for research on interventions to reduce HIV-associated stigma and its impact on the prevention and treatment of HIV/AIDS, particularly in low and middle income countries (LMICs). The proposed study has the highest public health significance: it uses a community-based participatory approach to engage local AYA to develop a digital crowdsourced HIV stigma reduction and self-testing intervention to reduce HIV stigma and increase HIV testing. Study Aim 1: To develop a crowdsourced digital HIV stigma reduction and self-testing intervention targeting AYA in Kazakhstan. Using a community-based participatory approach that engages local adolescents and young adults (AYA) and youth organizations, we will launch a national crowdsourcing contest in which AYA will design multimedia content to reduce HIV stigma in order to promote HIV testing among peers. Study Aim 2: To pilot test this crowdsourced HIV stigma reduction and self-testing intervention in a preliminary efficacy trial. We will assess the intervention's feasibility and acceptability and obtain preliminary estimates of its effects on decreasing HIV stigma (primary outcome) and increasing HIV testing (secondary outcome) among AYA in Kazakhstan who received the intervention compared to individuals who did not. Participants (n=168) will be randomized 1:1 to: 1) receive the winning multimedia crowdsourced HIV stigma reduction content and a link for HIV self-testing, or 2) receive standard Kazakhstan Ministry of Health HIV informational materials and a link for HIV self-testing.

Eligibility Criteria

Inclusion Criteria

  • Age 16-24
  • Report previous sex with another individual
  • Reside in Kazakhstan

Exclusion Criteria

  • Not willing to provide consent or not able to understand study procedures
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05107401). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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