N/A
N=216
Crowdsourcing to Reduce HIV Stigma Among Adolescents and Young Adults in Kazakhstan
Stigma, Social · HIV Testing
Bottom Line
View on ClinicalTrials.gov: NCT05107401 ↗Enrolled (actual)
216
Serious AEs
0.0%
Results posted
Dec 2024
Primary outcome: Primary: Mean Score Change in Total HIV Stigma Scale — 47.48; 47.89; 44.60; 47.32 units on a scale — p=0.083
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Digital Crowdsourced Intervention to Reduce HIV Stigma among Adolescents and Young Adults (Behavioral)
- Age
- Pediatric, Adult · 16+ yrs
- Sex
- All
- Sponsor
- Columbia University
- Primary completion
- Aug 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Score Change in Total HIV Stigma Scale |
47.48; 47.89; 44.60; 47.32 | 0.083 |
| SECONDARY Mean Change in Perceived HIV Test Stigma |
5.92; 5.70; 5.19; 5.64 | 0.032 sig |
| SECONDARY Mean Change in Perceived HIV Healthcare Stigma Subscale |
5.80; 5.90; 5.57; 5.89 | 0.48 |
| SECONDARY Mean Change in Fear & Judgement HIV Stigma Sub-scale |
11.12; 11.24; 10.56; 11.08 | 0.48 |
| SECONDARY Mean Change in Perceived Community HIV Stigma Subscale |
24.65; 25.05; 23.28; 24.74 | 0.37 |
| SECONDARY Uptake of HIV Self-test |
30; 18 | 0.099 |
Summary
This project will assess whether a digital crowdsourced intervention can reduce HIV stigma and promote HIV self-testing among adolescents and young adults (AYA). NIH has emphasized the need for research on interventions to reduce HIV-associated stigma and its impact on the prevention and treatment of HIV/AIDS, particularly in low and middle income countries (LMICs). The proposed study has the highest public health significance: it uses a community-based participatory approach to engage local AYA to develop a digital crowdsourced HIV stigma reduction and self-testing intervention to reduce HIV stigma and increase HIV testing.
Study Aim 1: To develop a crowdsourced digital HIV stigma reduction and self-testing intervention targeting AYA in Kazakhstan. Using a community-based participatory approach that engages local adolescents and young adults (AYA) and youth organizations, we will launch a national crowdsourcing contest in which AYA will design multimedia content to reduce HIV stigma in order to promote HIV testing among peers.
Study Aim 2: To pilot test this crowdsourced HIV stigma reduction and self-testing intervention in a preliminary efficacy trial. We will assess the intervention's feasibility and acceptability and obtain preliminary estimates of its effects on decreasing HIV stigma (primary outcome) and increasing HIV testing (secondary outcome) among AYA in Kazakhstan who received the intervention compared to individuals who did not. Participants (n=168) will be randomized 1:1 to: 1) receive the winning multimedia crowdsourced HIV stigma reduction content and a link for HIV self-testing, or 2) receive standard Kazakhstan Ministry of Health HIV informational materials and a link for HIV self-testing.
Eligibility Criteria
Inclusion Criteria
- Age 16-24
- Report previous sex with another individual
- Reside in Kazakhstan
Exclusion Criteria
- Not willing to provide consent or not able to understand study procedures
Data sourced from ClinicalTrials.gov (NCT05107401). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.