N/A
N=193
Can Exposure to Brief Messages Correct Misperceptions?
Beliefs
Bottom Line
View on ClinicalTrials.gov: NCT05129592 ↗Enrolled (actual)
193
Serious AEs
0.0%
Results posted
Mar 2024
Primary outcome: Primary: Change in Accuracy of Belief That Nicotine Causes Cancer — 52.6; 54.0; 39.2; 36.1 units on a scale — p=0.095
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Coherent corrective messages (Behavioral)
- Age
- Adult, Older Adult · 21+ yrs
- Sex
- All
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
- Primary completion
- Jan 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Accuracy of Belief That Nicotine Causes Cancer |
52.6; 54.0; 39.2; 36.1 | 0.095 |
| PRIMARY Change in Relative Harm Beliefs Regarding E-cigarettes |
34; 43; 38; 31; 6; 9 | 0.402 |
| PRIMARY Change in Relative Harm Beliefs Regarding NRT |
39; 47; 50; 40; 2; 5 | 0.980 |
| PRIMARY Change in Relative Harm Beliefs Regarding Very Low Nicotine Cigarettes |
28; 30; 25; 23; 13; 23 | 0.256 |
| PRIMARY Change in Inferential Beliefs Regarding Smokeless Tobacco |
17; 32; 22; 26; 22; 20 | 0.077 |
| PRIMARY Change in Inferential Beliefs Regarding Cigarillos |
6; 5; 6; 6; 33; 44 | 0.925 |
| PRIMARY Change in Beliefs About Intention to Switch Products |
60.6; 53.5; 56.4; 57.9 | 0.965 |
Summary
This study seeks to assess the efficacy of educational messages to correct misperceptions. A large proportion of the American population incorrectly believes that nicotine is the chemical responsible for causing cancer in tobacco products.1-3 This misconception may reduce the likelihood that established smokers who are unwilling or unable to quit tobacco product use completely will switch to less harmful non-combustible products. An online experiment will be used to test if corrective messages can reduce this misperception. The experiment will also test the effects of messages on beliefs about the relative harms of other tobacco products discussed in the message and accuracy of inferential beliefs. This will be accomplished by asking participants questions about two tobacco products that are not explicitly discussed in the messages. The experiment will test if the two components of "narrative coherence," a concept identified in previous reviews of misperception correction as effective,4-6 is effective at reducing misperceptions about nicotine. Component 1 provides an explanation for why the new information is correct and component 2 provides an explanation for how the false information came to be believed. This study will use a factorial design to test the efficacy of the component of coherence individually as well as together. Hypotheses and Research Questions:
RQ1: Will participants exposed to different corrective message conditions differ in increased accuracy of beliefs (a) that nicotine does not cause cancer, (b) regarding the relative risk of e-cigarettes compared to cigarettes, (c) regarding the relative risk of very low nicotine cigarettes (VLNC) compared to cigarettes and (d) regarding the relative risk of nicotine replacement therapy compared to cigarettes.
H1: Participants exposed to the nicotine corrective message with both components of coherence will be significantly more likely to increase accuracy of beliefs regarding the relative harms of (a) smokeless tobacco compared to cigarettes and (b) cigarillos relative to cigarettes compared to those exposed to messages with just one component or no components of coherence.
H2: Participants exposed to the nicotine corrective message with both components of coherence will be significantly more likely to increase their intention to switch completely to a noncombustible product compared to those exposed to messages with just one component or no components of coherence.
Eligibility Criteria
Inclusion Criteria
- Are established smokers (have smoked at least 100 cigarettes in their lifetime and currently smoke some or all days)
- Are 21 years of age or older (the legal age of tobacco purchase in the US)
- Have not completed the cognitive interview during message pre-testing.
- Rate their agreement with the following statement as at least 50 out of 100: "To what extent do you agree with the following statement: The substance nicotine causes cancer."
- Are registered with MTurk in the United States.
- Have completed >= 5, 000 HIITs within the MTurk system
- Have a HIIT approval rating of >= 97%
Exclusion Criteria
- Are not established smokers
- Are younger than 21 years of age
- Participated in cognitive interviews during message pre-testing
- Are not registered with MTurk in the US
- Have completed < 5,000 HIITS
- Have a HIIT approval rating of <97%
- Rate their agreement with the following statement as less than 50 out of 100: "To what extent do you agree with the following statement: The substance nicotine causes cancer."
Data sourced from ClinicalTrials.gov (NCT05129592). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.