N/A
Completed N=2,634
CONFIDENT: Supporting Long-term Care Workers During COVID-19
Source: ClinicalTrials.gov NCT05168800 ↗Enrolled (actual)
2,634
Serious AEs
0.0%
Results posted
Aug 2025
Primary outcomePrimary: COVID-19 Vaccine Confidence — 93; 106; 138 Participants — p=0.99
Summary
The CONFIDENT Study is an online three-arm randomized trial that aims to help long-term care workers in the United States feel more confident about the Coronavirus Disease 2019 (COVID-19) vaccines. The study will compare two different interventions to usual online information (website of the Centers for Disease Control and Prevention). The first intervention is a Dialogue-Based Webinar where people can interact and ask questions about the vaccines. The second intervention is a Social Media Website that will feature curated content about the vaccines from popular social media platforms.
Participants will be asked to completed four online surveys. The first survey will be completed pre-intervention and immediately upon study enrollment (Time 0). Participants will be randomized to a trial arm at the end of the Time 0 survey. Intervention follow-up surveys will be completed 3 weeks post-randomization (Time 1), three months post-randomization (Time 2), and 6 months post-randomization (Time 3).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY COVID-19 Vaccine Confidence |
93; 106; 138 | 0.99 |
| SECONDARY Change From Baseline to 3 Weeks Post-randomization in COVID-19 Vaccine Confidence |
42; 49; 62 | 0.93 |
| SECONDARY Change From Baseline to 3 Months Post-randomization in COVID-19 Vaccine Confidence |
57; 58; 55 | 0.22 |
| SECONDARY Change From Baseline to 6 Months Post-randomization in COVID-19 Vaccine Confidence |
52; 66; 62 | 0.65 |
| SECONDARY Net Promoter Score (COVID-19 Vaccination) |
-0.48; -0.52; -0.42 | 0.88 |
| SECONDARY Net Promoter Score (COVID-19 Booster Vaccination to Coworker) |
-0.59; -0.62; -0.51 | 0.95 |
| SECONDARY COVID-19 Vaccine Uptake (Any Dose) |
363; 383; 397 | 0.08 |
| SECONDARY COVID-19 Vaccine Uptake (Initial Series Completion) |
354; 374; 391 | 0.13 |
| SECONDARY COVID-19 Vaccine Uptake (Booster Completion) |
132; 144; 145 | 0.37 |
| SECONDARY COVID-19 Vaccine Intent (Initial Series) |
-0.76; -0.77; -0.62 | 0.92 |
| SECONDARY COVID-19 Vaccine Intent (Booster) |
-0.26; -0.16; -0.17 | 0.88 |
| SECONDARY COVID-19 Vaccine Intent (Future Vaccine Recommendations) |
-0.16; -0.17; -0.09 | 0.90 |
| SECONDARY Feeling Informed About the COVID-19 Vaccines |
2.68; 2.68; 2.89 | 1.00 |
| SECONDARY Identification of COVID-19 Vaccine Information and Misinformation |
2.19; 2.00; 2.30 | 0.88 |
| SECONDARY Trust in COVID-19 Vaccine Information From Different Sources |
1.71; 1.65; 1.76 | 0.82 |
| SECONDARY Change From Baseline in Secondary Outcomes |
— | — |
| SECONDARY As-treated Analyses of Primary and Secondary Outcomes |
— | — |
Eligibility Criteria
Inclusion Criteria
- at least 18 years of age
- can read, write, and understand English
- lives in the United States
- has worked in a long-term care setting in the past two years
- can provide information to confirm they have worked in a long-term care setting
- is not pregnant or breastfeeding
- at least somewhat worried about the COVID-19 vaccines and/or has not received a COVID-19 vaccine booster shot
Exclusion Criteria
- under 18 years of age
- cannot read, write, and understand English
- does not live in the United States
- has not worked in a long-term care setting in the past two years
- cannot provide information to confirm they have worked in a long-term care setting
- is pregnant or breastfeeding
- less than somewhat worried about the COVID-19 vaccines and has received at least one COVID-19 vaccine booster shot
Data sourced from ClinicalTrials.gov (NCT05168800). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.