N/A
Completed N=60
Comparison of the Substitution Between Different Tobacco/Nicotine Products as a Function of Tobacco-user Type
Cigarette Smoking · Nicotine Vaping
Source: ClinicalTrials.gov NCT05177848 ↗
Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Sep 2024
Primary outcomePrimary: Nicotine/Tobacco Products Substitution — 12.11; 4.82; 25.28; 17.08 mg of nicotine purchased — p=0.9793
Summary
This study will investigate the relative appeal (abuse liability) of novel tobacco products, how the appeal is modulated by relative price, user type, and how novel products may substitute for one another.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Nicotine/Tobacco Products Substitution |
12.11; 4.82; 25.28; 17.08; 19.70; 10.73 | 0.9793 |
| PRIMARY Cigarette Demand |
212.39; 193.58; 221.66; 163.28; 186.03; 231.96 | 0.29 |
Eligibility Criteria
Inclusion Criteria
- Provide informed consent
- Be at least 21 years of age or older
- Provide a breath sample for measuring carbon monoxide (CO ≥ 8 ppm)
- Stable tobacco use patterns for at least three months
- Be willing to sample NVPs, HTPs, and NPPs
- For exclusive cigarette smokers: smoke at least 10 cigarettes daily and do not use NVPs regularly (no more than 9 times in the last month)
- For dual cigarette/NVP users: smoke at least 5 cigarettes daily and use NVPs for at least 3 times in a week (report use of closed nicotine salt system)
Exclusion Criteria
- Have plans to move out of the area
- Have a serious or unstable physical or mental health condition
- Taking a tobacco cessation medication or medication that interferes with nicotine metabolism, motivation or reinforcement
- Report concrete, immediate plans to alter/quit using their usual nicotine products at the beginning of the study
Data sourced from ClinicalTrials.gov (NCT05177848). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.