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N/A N=123 Randomized Health Services Research

Uncontrolled Hypertension Among the Homeless

Hypertension

Enrolled (actual)
123
Serious AEs
0.0%
Results posted
Sep 2025
Primary outcome: Primary: Blood Pressure — 135.36; 136.19; 89.67; 92.38 mmHG — p=0.006

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
mHealth for Hypertension in Homeless Persons (Behavioral)
Age
Adult, Older Adult · 21+ yrs
Sex
All
Sponsor
George Washington University
Primary completion
Sep 2025

Outcome Measures

OutcomeResultp-value
PRIMARY
Blood Pressure
135.36; 136.19; 89.67; 92.38 0.006 sig
PRIMARY
Medication Adherence
83.3; 50 0.14
PRIMARY
Appointment Attendance
46.08; 57.41 0.32
SECONDARY
Number of Participants Who Completed Interviews
13; 6; 10

Summary

This study is designed to assess the effect of implementing a mobile health (mHealth) strategy using text messaging for hypertension (HTN) management among hypertensive homeless persons with uncontrolled blood pressure age 21 or older in shelter-clinics in New York City (NYC). The study uses a randomized clinical trial design (homeless, n=120) and semi-structured interviews (homeless, n=30; providers, n=20). The control group will receive text messages for usual standard care/healthy lifestyle during a 6-month follow-up period. The intervention group will receive text messages geared towards both standard care/healthy lifestyle and blood pressure control. At the end of study period, the investigators will assess changes in blood pressure (BP) measurements, adherence to clinic visits, and adherence to medication, and the investigators will compare them between the two groups. Qualitative interviews with both patients and providers who provide services to the homeless in shelter settings will develop a better understand barriers and opportunities regarding BP control. The investigators hypothesize that those individuals randomized to the intervention will experience a reduction in blood pressure (8mmHg systolic BP or diastolic BP) and will exhibit better adherence to blood pressure medications and appointments compared to the control group.

Eligibility Criteria

Inclusion Criteria

  • Currently experiencing homelessness
  • Current diagnosis of hypertension
  • SBP above 140mmHg or DBP above 90mmHg at most recent clinic visit
  • English or Spanish speaking
  • Currently presenting to Project Renewal shelter-clinics for medical care
  • Connected to multidisciplinary social and health services at Project Renewal

Exclusion Criteria

  • Pregnant or within 3 months post-partum
  • Heart attack or stroke within previous 6 months
  • History of aortic aneurysm
  • Diagnosis of end-stage renal disease or currently on dialysis
  • Inability to read or respond to SMS texts
  • Any condition preventing participants from providing informed consent
  • SBP >175mmHg or DBP >105mmHg unless medical provider determines patient has no symptoms suggesting a hypertensive emergency or urgency
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05187013). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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