N/A
N=182
Telerehabilitation in People With Long COVID
COVID-19
Bottom Line
View on ClinicalTrials.gov: NCT05205460 ↗Enrolled (actual)
182
Serious AEs
0.0%
Results posted
Mar 2025
Primary outcome: Primary: Change in Exercise Capacity: Peak Oxygen Uptake (VO2peak) From Baseline to 12 Weeks — 2.4; 1.7 ml/kg/min
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Home-based telerehabilitation (Device); Education and self-exercise (Behavioral)
- Age
- Adult, Older Adult · 20+ yrs
- Sex
- All
- Sponsor
- Tri-Service General Hospital
- Primary completion
- Apr 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Exercise Capacity: Peak Oxygen Uptake (VO2peak) From Baseline to 12 Weeks |
2.4; 1.7 | — |
| PRIMARY Change in Exercise Capacity: Workload (Watt) From Baseline to 12 Weeks |
7.0; 7.3 | — |
| PRIMARY Change in Exercise Capacity: Anaerobic Threshold (AT) From Baseline to 12 Weeks |
1.2; 1.0 | — |
| PRIMARY Change in Lung Function: Forced Expiratory Volume 1 (FEV1) From Baseline to 12 Weeks |
0.0; 0.0 | — |
| PRIMARY Change in Lung Function: Forced Vital Capacity (FVC) From Baseline to 12 Weeks |
0.0; -0.1 | — |
| PRIMARY Change in Lung Function: FEV1/FVC % From Baseline to 12 Weeks |
-1.2; 0.7 | — |
| PRIMARY Change in Ventilation/ Perfusion Abnormalities (VE/VCO2) From Baseline to 12 Weeks |
-0.1; 0.8 | — |
| PRIMARY Change in Left Ventricular Function: O2 Pulse From Baseline to 12 Weeks |
0.5; 0.6 | — |
| PRIMARY Change in Heart Rate Recovery From Baseline to 12 Weeks |
1.1; 1.3; 2.3; 3.2 | — |
| SECONDARY Change in Physical Activity Amounts: Taiwan Version of the International Physical Activity Questionnaire From Baseline to 12 Weeks |
-13.6; 302.4; -87.6; 103.7; -1239; 406 | — |
| SECONDARY Change in Confidence Level of Exercise: Questionnaire of Self-Efficacy Items From Baseline to 12 Weeks |
1.2; -1.1 | — |
| SECONDARY Change in Health-Related Quality of Life: Taiwan Version of World Health Organization Quality-of-Life Questionnaire From Baseline to 12 Weeks (WHOQOL-BREF) |
0.5; 0.2; 0.4; 0.1; 0.3; 0.3 | — |
| SECONDARY Change in Sleep Quality: Pittsburgh Sleep Quality Index (PSQI) From Baseline to 12 Weeks |
0.9; 0.7 | — |
Summary
The aim of our study is to investigate the effectiveness of telerehabilitation in Post-COVID patients.
Eligibility Criteria
Inclusion Criteria
Individuals who had been diagnosed with COVID-19 positive and whose last PCR test or rapid antigen test was negative with the following criteria:
- aged between 20 to 80 years old
- persistent symptoms at least 4 weeks after recovery from COVID-19 infection, including any of the following symptoms: dyspnea, fatigue, cough, headache, chest tightness, palpitations, loss of smell, anxiety, insomnia, brain fog or joint pain
- able to speak and understand Mandarin
- able to walk including those who need the walking aid
- had mobile phones and could easily access the Internet
Exclusion Criteria
- a history of chronic obstructive pulmonary disease or other respiratory diseases
- a history of arrhythmia, cancer, end-stage renal disease with dialysis, being diagnosed with mental illness, recent stroke within 6 months
- inability to participate because of comorbid neurological or musculoskeletal conditions that produce moderate to severe physical disability
- need all day oxygen support
Data sourced from ClinicalTrials.gov (NCT05205460). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.