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Phase 4 N=60 Randomized Triple-blind Treatment

Subacromial Injection of Epinephrine Improves Visualization in Shoulder Arthroscopy

Shoulder Arthroscopy

Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Nov 2023
Primary outcome: Primary: Surgeon-rated Visual Clarity as Assessed by the Visual Analog Scale — 8.3; 7.5 score on a scale

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
Bupivacaine with Epinephrine (Drug); Bupivacaine alone (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
The University of Texas Health Science Center, Houston
Primary completion
Aug 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Surgeon-rated Visual Clarity as Assessed by the Visual Analog Scale
8.3; 7.5
PRIMARY
Percentage of Participants for Whom Intra-operative Arthroscopic Pump Pressure Was Increased to 45mmHg or Higher During the Surgical Procedure
22; 23
SECONDARY
Intraoperative Mean Arterial Pressure
70.5; 71.3
SECONDARY
Total Operative Time
62; 64
SECONDARY
Number of Subjects Who Experience Intraoperative Adverse Events
0; 0
SECONDARY
Number of Subjects Who Experience Post Operative Adverse Events
0; 0

Summary

The purpose of this study is to evaluate surgeon-rated visual clarity and the need for increased irrigation pump pressure during arthroscopic shoulder surgery and to evaluate mean arterial pressure, operative time, and any adverse events that occur during arthroscopic shoulder surgery.

Eligibility Criteria

Inclusion Criteria

  • Undergo arthroscopic shoulder surgery in the seated upright (beach-chair) position requiring visualization within the subacromial space

Exclusion Criteria

  • Are unable to provide informed consent
  • Non-English speaker
  • Have a history of adverse medication reaction to epinephrine
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05244525). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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