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N/A N=435 Randomized Basic Science

Application of Ideal Binary Masking to Disordered Speech

Hearing Loss, Sensorineural · Dysarthria

Enrolled (actual)
435
Serious AEs
0.0%
Results posted
Mar 2025
Primary outcome: Primary: Percent Correct Speech Intelligibility — 69; 63 percentage of words correctly reported

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Ideal binary mask (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Utah State University
Primary completion
Dec 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Percent Correct Speech Intelligibility
69; 63

Summary

Dysarthria and hearing loss are communication disorders that can substantially reduce intelligibility of speech and the addition of background noise adds a further challenge. This proposal utilizes an established signal processing technique, currently exploited for improved understanding of speech in noise for listeners with hearing loss, to investigate its potential application to overcome speech-in-noise difficulties for listeners understanding dysarthric speech. Successful completion of this project will demonstrate proof-of-concept for the application of this signal processing technique to dysarthric speech in noise, and inform the development of an R01 proposal to perform a large-scale evaluation of the technology, and clinically meaningful implications, in a broad range of disordered speech types and severities.

Eligibility Criteria

Inclusion Criteria:INCLUSION CRITERIA for All Participants

  • Native speakers of American English
  • No history of speech or language impairment
  • No significant prior contact with persons having neurogenic speech disorders

INCLUSION CRITERIA for Participants with Normal Hearing

  • 18 to 70 years of age
  • Auditory thresholds of 20 dB HL or better bilaterally at octave frequencies from 250-8000 Hz (if under 55 years of age)
  • Auditory thresholds of 25 dB HL or better bilaterally at octave frequencies from 250-4000 Hz (if over 55 years of age)

INCLUSION CRITERIA for Participants with Sensorineural Hearing Loss

  • 18 to 90 years of age

Exclusion Criteria

  • EXCLUSION CRITERIA for All Participants
  • Mild or profound hearing loss
  • Conductive or mixed hearing loss
  • Asymmetric hearing loss
  • Obvious concomitant cognitive or mental impairment
  • Unable to achieve upward of 20% words correct
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05244603). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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