Phase 4
N=152
PENG Block Versus LP Block for THA Postop Pain
Pain, Postoperative · Hip Pain Chronic
Bottom Line
View on ClinicalTrials.gov: NCT05261009 ↗Enrolled (actual)
152
Serious AEs
2.0%
Results posted
Mar 2024
Primary outcome: Primary: Numeric Rating Scale (NRS) Pain Score — 4.0; 2.8 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 4
- Interventions
- Peri-capsular Nerve Group (PENG) (Drug); Lumbar Plexus Block (LPB) (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Wake Forest University Health Sciences
- Primary completion
- Jul 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Numeric Rating Scale (NRS) Pain Score |
4.0; 2.8 | — |
| SECONDARY NRS Pain Score |
5.7; 4.6 | — |
| SECONDARY NRS Pain Score |
5.7; 4.6 | — |
| SECONDARY NRS Pain Score |
5.7; 4.6 | — |
| SECONDARY Time in Minutes Until Opioid Administration |
464.98; 394.69 | — |
| SECONDARY Motor Strength |
3.5; 2.4 | — |
| SECONDARY Distance Ambulated |
59.1; 43.9 | — |
Summary
The purpose of this randomized, double blinded, prospective study is to compare the postoperative analgesia provided by the PENG block to that provided by the LPB for patients undergoing primary anterior approach THA.
Eligibility Criteria
Inclusion Criteria
- elective primary total hip arthroplasty surgery anterior approach
- provided informed consent
- no contraindications to medications used in providing the analgesic blocks
Exclusion Criteria
- contraindications to regional anesthesia, such as an allergy to amide local anesthetics
- pre-existing coagulopathy or thrombocytopenia <100,000
- refusal of analgesic block for pain management
- presence of an progressive lower extremity neurological deficit
- localized or systemic infection
- chronic use of high dose opioid analgesics (defined as daily use greater than 60 mg oxycodone equivalents)
- pregnant
- refusal of consent
Data sourced from ClinicalTrials.gov (NCT05261009). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.