Phase 4
Completed N=103
Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures
Eyelid Tumor · Eyelid Bump · Eyelid Deformity · Eyelid Abscess
Source: ClinicalTrials.gov NCT05294640 ↗
Enrolled (actual)
103
Serious AEs
0.0%
Results posted
Jun 2025
Primary outcomePrimary: Pain on Injection — 2.8; 3.6 score on a scale
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
The investigators aim to assess whether bacteriostatic saline provides the same level of anesthesia as traditional local anesthesia while reducing pain associated with medication infusion in minor eyelid procedures
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Pain on Injection |
2.8; 3.6 | — |
| PRIMARY Pain of Procedure |
4.9; 2.0 | — |
| SECONDARY Number of Lesions That Needed Additional Anesthesia to Complete Procedure |
33; 5 | — |
| SECONDARY Bleeding Level |
29; 33; 25; 16; 4; 0 | — |
Eligibility Criteria
Inclusion Criteria
- Age >=18 years old
- Undergoing clinic-based periocular procedure
Exclusion Criteria
- Any other topical, oral or intravenous sedating medications given alongside procedure
- Allergy to saline, lidocaine or epinephrine
- Unable to provide consent due to cognitive impairment
Data sourced from ClinicalTrials.gov (NCT05294640). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.