N/A
N=74
Impact of a Family History of Hypertension and Physical Activity on Left Ventricular Mass
Genetic Predisposition · Genetic Hypertension
Bottom Line
View on ClinicalTrials.gov: NCT05334355 ↗Enrolled (actual)
74
Serious AEs
0.0%
Results posted
Feb 2025
Primary outcome: Primary: Left Ventricular Mass — 155.1680523; 129.5013331 gram
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Family history of hypertension (Other)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- Montclair State University
- Primary completion
- Feb 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Left Ventricular Mass |
155.1680523; 129.5013331 | — |
Summary
This is a retrospective analysis of data collected within two previous studies. The data has been combined and used to investigate the impact of having a family history of hypertension on left ventricular muscle mass with and without controlling for moderate and vigorous intensity physical activity frequency per week. The hypothesis was that in a sample of mostly active participants, no differences in left ventricular mass between family history of hypertension groups would be observed, but the positive family history of hypertension group would have elevated left ventricular mass compared to the negative family history of hypertension group following statistical control of activity frequency.
Eligibility Criteria
Inclusion Criteria
- Generally healthy
Exclusion Criteria
- Known hypertension, cardiovascular disease, current pregnancy, current infectious disease, diabetes mellitus, kidney disease, a history of cancer, pulmonary disease, history of a stroke, obesity (for most people this means a body mass index greater than 30), or any life threatening chronic conditions
Data sourced from ClinicalTrials.gov (NCT05334355). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.