N/A
N=35
The Effect of Hypotensive Anesthesia on Hemoglobin Levels During Total Knee Arthroplasty
Anesthesia
Bottom Line
View on ClinicalTrials.gov: NCT05340751 ↗Enrolled (actual)
35
Serious AEs
0.0%
Results posted
Jan 2023
Primary outcome: Primary: The Hemoglobin (in g/dl) Levels — 12.2; 12.0; 11.9; 11.8 g/dl
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Blood drawn (Diagnostic_test)
- Age
- Adult, Older Adult · 40+ yrs
- Sex
- All
- Sponsor
- Hospital for Special Surgery, New York
- Primary completion
- Sep 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Hemoglobin (in g/dl) Levels |
12.2; 12.0; 11.9; 11.8; 12.0; 11.6 | — |
| PRIMARY Hematocrit (g/dL) Levels |
36.8; 36; 35.4; 34.7; 35.1; 35.3 | — |
Summary
The current study investigates the effect of hypotensive anesthesia on patient hemoglobin levels during primary total knee arthroplasty. Considering that because of the tourniquet there is no blood loss during the first 60 minutes of the procedure changes in hemoglobin during the first 60 minutes should be primarily related to decrease in blood pressure and secondary to fluid loading during hypotensive anesthesia.
Eligibility Criteria
Inclusion Criteria
- Non- inflammatory degenerative joint disease of the knee
- Patients scheduled for unilateral primary total Knee arthroplasty
- Age between 40 and 80 years
- Hypotensive spinal-epidural anesthesia with systolic BP 1.5)
- Aortic or mitral valve disease
- Pulmonary hypertension
- Revision Knee Surgery
- Inadequate intravenous fluid substitution during the procedure 1.5L during 60 minutes.
Data sourced from ClinicalTrials.gov (NCT05340751). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.