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Phase 2 N=30 Randomized Triple-blind Treatment

The Efficacy Of SCH1 In The Treatment Of Acute Infectious Conjunctivitis

Acute Infectious Conjunctivitis (Disorder)

Enrolled (actual)
30
Serious AEs
0.0%
Results posted
Apr 2026
Primary outcome: Primary: Complete Clinical Resolution — 9; 0 Participants

Study Design & Population

Study type
Interventional
Phase
Phase 2
Interventions
SCH-1 (Drug); Placebo (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Sacsh
Primary completion
Mar 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Complete Clinical Resolution
9; 0

Summary

The objective of this study is to evaluate the efficacy of Sasch1, a novel anti-infective eyedrop, in the treatment of acute infectious conjunctivitis.

Eligibility Criteria

Inclusion Criteria

  • Conjunctivitis (as defined below) within 72 hours of initial ocular symptoms.
  • At least 18 years of age.
  • Subjects capable of understanding the purpose and risks of the study, and able to give informed consent.
  • Conjunctivitis diagnosis defined as presence of the two cardinal signs of acute conjunctivitis- 1) bulbar conjunctival injection and 2) conjunctival discharge/exudates.
  • A three-point rating scale (0=absent, 1=mild, 2=moderate, 3=severe) will be employed to grade conjunctival discharge/exudates.
  • All patients will require a rating of 1(mild) or greater for conjunctival discharge/exudates.
  • Patients will require a rating of 1 (mild) for bulbar conjunctival injection.

Exclusion Criteria

  • Conjunctivitis greater than 72 hours after initial ocular symptoms
  • Corneal ulcer, endophthalmitis, or any other confounding infection of the eye
  • Patients taking topical anti-inflammatory medications on a chronic basis
  • Known steroid glaucoma responders
  • Active herpes ocular infection
  • Pregnant women
  • Known allergy to chlorhexidine
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05356793). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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