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N/A N=34,047 Randomized Single-blind Screening

Behavioural Science Messages in Breast Cancer Screening

Breast Cancer

Enrolled (actual)
34,047
Serious AEs
0.0%
Results posted
Jan 2025
Primary outcome: Primary: No. of Participants Taking up Breast Cancer Screening at Three Months- Intention to Treat — 2225; 2064; 2137 participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Behavioural Message (Behavioral); Behavioural Message + Video (Behavioral); Usual Care Message (Other)
Age
Adult, Older Adult · 50+ yrs
Sex
Female
Sponsor
Imperial College London
Primary completion
Jan 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
No. of Participants Taking up Breast Cancer Screening at Three Months- Intention to Treat
2225; 2064; 2137
PRIMARY
No. of Participants Taking up Breast Cancer Screening at Three Months- Per Protocol
2073; 1899; 1977
SECONDARY
No. of Participants Taking up Breast Cancer Screening, Three Months After the Initial Invitation Amongst Those From Sociodemographic Groups (Deprivation, Ethnicity)
1379; 1276; 1303; 1206; 1194; 1243
SECONDARY
No. of Participants Taking up Uptake of Breast Cancer Screening, Three Months After the Initial Invitation Letter, Amongst Those Given Different Invitation Types.
4104; 3909; 3978
SECONDARY
No. of Participants Taking up Breast Cancer Screening, Three Months After the Initial Invitation Letter, Amongst Those With Different Screening History
406; 379; 394; 1820; 1686; 1743

Summary

Breast cancer is the most common cancer in the United Kingdom, with 1 in 8 women affected during their lifetime. Whilst survival rates are high, the 5-year survival rate is 72% higher with the earliest stage breast cancer, compared to the latest disease stage. The National Health Service Breast Screening Programme invites women aged 50 to 70 years old every three years to a mammogram. By enabling earlier detection, it is estimated that the National Health Service Breast Screening Programme saves 1300 lives per year. Despite the potential benefits of breast cancer screening, attendance is falling. Behavioural Science is a field of study concerning understanding the processes underpinning human action. Behavioural theories, such as the Capability Opportunity Motivation-Behaviour model. Recent studies have shown the application of behavioural science to screening may also facilitate uptake of invitations. However, the use of plain text messages limits which behavioural determinants can be feasibly addressed, and what techniques can be used. Video messages can allow for more complex and a broader range of behavioural change techniques to be incorporated, and therefore have greater impact upon attendance. Whilst behavioural science-informed messages have previously been trialed by groups to facilitate breast screening attendance, their effectiveness has been variable. One of the reasons for this, is that text messages are of limited length and formatting capability, thus restricting the number of behavioural change techniques that can be included. Moreover, some behavioural techniques are more complex than others, and plain text can limit the extent to which these can be feasibly incorporated. Video messaging provides a delivery mechanism that may enable more complex, and different combinations to be trialed. There is however, a paucity of data regarding the impact of sending a video-based behavioural science message upon attendance rates at breast cancer screening programmes. This study looks to investigate the impact of a video-message, compared to behavioural science-based text messages and standard reminder messages. The primary object is to determine the impact of behavioural science informed (1) video and (2) text messages compared to usual care, upon uptake of breast cancer screening. Secondary objectives involve how this impact on attendance differs between population subgroups including people from differing demographic groups.

Eligibility Criteria

The inclusion criteria will match those used by the National Health Service Breast Screening Programme, as all invitations will come directly from the programme, as per usual care. These include:

  • Aged between 50 to 70 at the time of invitation
  • Lives within London screening region
  • Registered as female with primary care physician

The exclusion criteria will match those used by the National Health Service Breast Screening Programme, as all invitations will come directly from the programme, as per usual care. These include:

  • Previous attendance at breast screening in the current (3-year cycle)
  • Opted out of receiving text messages
  • Opted out of screening
  • Previous bilateral mastectomy
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05395871). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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