N/A
Completed N=26
Theta Phase-specific TMS to Modulate Prefrontal Activity
Approach/Avoidance Behavior
Source: ClinicalTrials.gov NCT05416138 ↗
Enrolled (actual)
26
Serious AEs
0.0%
Results posted
Dec 2025
Primary outcomePrimary: Reaction Times in the Approach/Avoidance Test — 36.8; 12.4 milliseconds
Summary
The purpose of this study is to evaluate the causal link between the phase of ongoing theta oscillations in the prefrontal cortex and approach/avoidance (Ap/Av) behavior in adults using theta phase-specific transcranial magnetic stimulation (TMS).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Reaction Times in the Approach/Avoidance Test |
36.8; 12.4 | — |
| SECONDARY Amplitude of TMS Evoked Potentials |
1.3; 0.2 | — |
Eligibility Criteria
Inclusion Criteria
- Age between 18 and 65 years old.
- Confident level of English language.
Exclusion Criteria
- Chronic condition that requires pharmacological treatment over the course of study participation.
- Metallic or electric implant in the head, neck, or chest area or otherwise MRI-noncompatible implants.
- History or evidence of seizures, head injuries with loss of consciousness, chronic neurological or mental disorder.
- Pregnancy or breast-feeding.
- History or evidence of alcohol or drug addiction.
Data sourced from ClinicalTrials.gov (NCT05416138). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.