N/A
N=601
Le Kip Kip: A Campaign to Change Social Norms and Build Sustainable Demand for PrEP Among Women in South Africa
Pre-exposure Prophylaxis · HIV Infections
Bottom Line
View on ClinicalTrials.gov: NCT05417620 ↗Enrolled (actual)
601
Serious AEs
0.0%
Results posted
Jul 2025
Primary outcome: Primary: Number of Service-users Who Initiate PrEP Uptake Within the TB HIV Care Programme — 17949; 3091; 924; 925 Participants — p=0.707
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Social Media Campaign (Behavioral); PrEP Champions (Behavioral); Community Mobilization (Behavioral); Standard of Care (Other)
- Age
- Pediatric, Adult, Older Adult · 15+ yrs
- Sex
- Female
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
- Primary completion
- Sep 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Service-users Who Initiate PrEP Uptake Within the TB HIV Care Programme |
17949; 3091; 924; 925; 2279 | 0.707 |
| SECONDARY Proportion of PrEP Persistence at 1-month Within the TB HIV Care Programme |
42.88; 27.60 | — |
| SECONDARY Proportion of PrEP Persistence at 4 Months Within the TB HIV Care Programme |
29.48; 15.56 | — |
| SECONDARY Number of Participants Who Found Intervention Acceptable |
137 | — |
| SECONDARY Adoption as Assessed by Number of Facebook Page Visits by Unique Users |
52608 | — |
| SECONDARY Total Cost |
223736 | — |
| SECONDARY Penetration as Assessed by Number of Participants Who Report Engagement With Campaign Among Social Support Networks |
68; 106; 41 | — |
| SECONDARY Fidelity as Assessed by Percentage of On-Schedule Posts |
300; 100 | — |
| SECONDARY Adoption as Assessed by Number of Views by Unique Users |
576384; 44081 | — |
| SECONDARY Adoption as Assessed by Number of Ad Clicks |
35934 | — |
| SECONDARY Fidelity as Assessed by Programme Logs Completed |
49.2; 86.4 | — |
Summary
The purpose of this study is to evaluate the impact of a social media campaign and community engagement activities to promote pre-exposure prophylaxis (PrEP) use among young women and to influence community norms around PrEP in South Africa. To do this, the investigative team will analyze PrEP initiation and retention data from the study's implementing partner, TB HIV Care, a non-profit organization providing PrEP to marginalized young women in South Africa. The effect of the social media campaign and community engagement will be tested using a short duration cluster randomized trial (CRT).
Eligibility Criteria
Inclusion Criteria
- Eligible to take PrEP per TB HIV Care programmatic criteria
- Engaged in TB HIV Care HIV prevention program
Exclusion Criteria
- Not eligible for PrEP (not at risk for HIV) per TB HIV Care programmatic criteria
Data sourced from ClinicalTrials.gov (NCT05417620). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.