N/A N=251 Randomized Health Services Research

COVID-19 Vaccine Uptake Trial

Vaccination Refusal · COVID-19

Bottom Line

View on ClinicalTrials.gov: NCT05419232 ↗

Enrolled (actual)

251

Serious AEs

0.0%

Results posted

Apr 2025

Primary outcome: Primary: Vaccine Uptake — 1; 3; 1; 0 Participants

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Short Message Service (SMS) + Website Link Strategy (Other); Phone Call with Peer Strategy (Other)
Age: Pediatric, Adult, Older Adult
Sex: All
Sponsor: Washington University School of Medicine
Primary completion: Dec 2023

Outcome Measures

Outcome	Result	p-value
PRIMARY Vaccine Uptake	1; 3; 1; 0; 2; 0	—
SECONDARY Vaccinated or Indicated They Would Receive Vaccine	7; 7; 4; 1; 2; 0	—

Summary

The goal of this study is to assess the best COVID-19 vaccine uptake strategy among students, staff and household members that have not been vaccinated. There is a multitude of recommendations present that highlight different vaccination strategy; however, it is still unclear which strategy is best to increase COVID-19 vaccination rates. We will compare the effectiveness and acceptance of two different communication strategies among unvaccinated students, staff, and their household members.

Eligibility Criteria

Inclusion Criteria

Is not up to date with their COVID-19 vaccinations per CDC guidelines
is considered eligible by the CDC at the time of enrollment to receive a COVID-19 vaccine
is a staff, student, or household member of staff or student of one of the participating school districts OR a resident of St. Louis City or St. Louis County

Exclusion Criteria

Is currently up to date with their COVID-19 vaccinations per CDC guidelines
ineligible to receive any COVID-19 vaccine due to medical history or age
is not a staff or student, or household member of staff or student of one of the participating school districts AND is not a resident of St. Louis City or St. Louis County
participant (or their parents/LAR) do not provide consent.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05419232). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.