N/A Completed N=18 Randomized Treatment

Vagal Nerve Stimulation for Post COVID Fatigue

COVID · Fatigue · Headache

Source: ClinicalTrials.gov NCT05445427 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Mar 2025

Primary outcomePrimary: Change in Post-COVID Functional Status Score — 0.1; 0.3 units on a scale — p=0.544

Summary

The purpose of this study is to evaluate the impact of vagal nerve stimulation on patients with post COVID syndrome who have fatigue and headache.

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Post-COVID Functional Status Score	0.1; 0.3	0.544
SECONDARY Change in PROMIS Fatigue Scale T Score	-5.4; -1.9	0.292

Eligibility Criteria

Inclusion Criteria

Presence of fatigue and post exertional malaise.
Presence of headache
Clinical diagnosis of post COVID syndrome.
They have consented to participate in the study
They have the ability to participate in all aspects of the study.

Exclusion Criteria

Pregnant.
Prior adverse reaction to 14FDG.
Active implantable medical device e.g. pacemaker, hearing aid implant
Metallic device e.g. stent, orthopedic hardware in neck
Using another electronic device at the same time e.g. TENS, mobile phone.
Any other condition deemed exclusionary by the study principal investigator

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05445427). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.