N/A
N=28
Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest
Cardiopulmonary Arrest · Pediatric ALL · Resuscitation
Bottom Line
View on ClinicalTrials.gov: NCT05474170 ↗Enrolled (actual)
28
Serious AEs
0.0%
Results posted
Apr 2026
Primary outcome: Primary: Median Alveolar Ventilation — 276; 370 ml
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- AHA resuscitation sequence (Other); ERC resuscitation sequence (Other)
- Age
- Pediatric, Adult, Older Adult
- Sex
- All
- Sponsor
- Geneve TEAM Ambulances
- Primary completion
- Sep 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Median Alveolar Ventilation |
276; 370 | — |
| SECONDARY The Total Number of Ventilations |
10; 13 | — |
| SECONDARY The Percentage of Ventilations Within, Above and Below the Target Volume |
0; 4; 75; 76; 0; 3 | — |
| SECONDARY The Alveolar Ventilation Obtained Without Taking Ventilation Volumes Over 70 ml Into Account, Reported as the Median Value of the Ventilations Over the First Minute. |
271; 365 | — |
| SECONDARY The Percentage of Compressions of Correct Depth |
0; 0; 89; 91 | — |
| SECONDARY The Percentage of Chest Compressions Within, Above and Below the Target Rate. |
3; 0; 90; 91; 0; 1 | — |
| SECONDARY The Chest Compression Fraction (CCF) |
66; 57 | — |
| SECONDARY The Percentage of Compressions With Adequate Chest Recoil |
76; 93 | — |
Summary
The International Liaison Committee on Resuscitation regularly publishes a Consensus on Science with Treatment Recommendations but guidelines can nevertheless differ when knowledge gaps persist. In case of pediatric cardiac arrest, the American Heart Association recommends following the adult resuscitation sequence i.e., starting with chest compressions. Conversely, the European Resuscitation Council advocates the delivery of 5 initial rescue breaths before starting chest compressions. Carrying out a randomized trial in children in cardiac arrest to assess the impact of these strategies would prove particularly challenging and ethical concerns may prevent such a trial from being performed. This will be a superiority, cross-over randomized trial whose goal is to determine the impact of these 2 resuscitation sequences on alveolar ventilation in a pediatric model of cardiac arrest. While not definitive, its results could help fill part of the current knowledge gap.
Eligibility Criteria
Inclusion Criteria
- Being issued from one of the following profession: Emergency medical technicians (EMTs), paramedics, nurses and physicians
Exclusion Criteria
- Being member of the study team
Data sourced from ClinicalTrials.gov (NCT05474170). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.