N/A N=2,454 Health Services Research

Testing Implementation Strategies to Improve Delivery of PrEP for Pregnant and Postpartum Women in Kenya

Pre-Exposure Prophylaxis · HIV Infections · Pregnancy Related

Bottom Line

View on ClinicalTrials.gov: NCT05482360 ↗

Enrolled (actual)

2,454

Serious AEs

0.0%

Results posted

Feb 2025

Primary outcome: Primary: Change in PrEP Penetration — 13; 23; 35; 3 Participants

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: PrEP Optimization Interventions (Other)
Age: Pediatric, Adult, Older Adult · 15+ yrs
Sex: Female
Sponsor: University of Washington
Primary completion: Dec 2023

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in PrEP Penetration	13; 23; 35; 3; 49; 23	—
PRIMARY Change in PrEP Fidelity	9; 8; 15; 1; 23; 14	—
PRIMARY Timeliness of Services	15; 14; 13; 12; 14; 15	—
PRIMARY Waiting Time	47; 33; 37; 33; 47; 32.5	—
PRIMARY HCW Acceptability	18.5; 18; 20	—
PRIMARY Health Care Worker (HCW) Appropriateness	18; 19; 20	—
PRIMARY Client Satisfaction	22; 22; 21; 20; 22; 21	—
SECONDARY PrEP Uptake	2; 2; 2; 0; 7; 4	—
SECONDARY PrEP Continuation	2; 6; 2; 0; 5; 8	—
SECONDARY Client PrEP Knowledge	3; 6; 0; 0; 0; 0	—
SECONDARY PrEP Adherence	—	—
SECONDARY PrEP Efficiency	—	—

Summary

This study tests strategies for improving PrEP implementation in maternal and child health clinics using an interrupted time series.

Eligibility Criteria

Inclusion Criteria

Women receiving Maternal and Child Health (MCH) services HCW participating in satisfaction surveys

Exclusion Criteria

Unwilling or unable to provide informed consent

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05482360). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.